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Introduction: The opioid epidemic in the United States continues to escalate and contribute to potentially preventable deaths. Because many opioid addictions begin with prescription medication, focus on limiting exposure and decreasing availability are essential. This study identifies the average number of opioid pills consumed following primary total knee and hip arthroplasty (TKA and THA) at our institution in opiate-naive patients to provide an estimate of medication required. We hypothesized that the average number of pills consumed for both TKA and THA was significantly less than the amount prescribed at discharge.
Methods: We prospectively evaluated 99 consecutive patients undergoing primary TKA (51) and THA (48). Patient characteristics and opioid prescription information were pulled from review of medical records. Patients brought remaining pain medications to their first follow-up visit (30 days). We calculated the number of pills consumed. Pill consumption was converted into opioid morphine equivalents. Current pain level and the need for pain medication refill were assessed.
Results: Median number of pills prescribed over 30 days was 90 for both TKA and THA. Median number of pain pills consumed was 67 in TKA patients and 37 in THA patients (P < 0.001). Higher oral morphine equivalent consumption was seen in TKA patients compared with THA patients. Mean pain scores of TKA and THA patients were 3.2 and 1.8, respectively (P = 0.002). Also, TKA patients were 5 times more likely to require a refill (P = 0.006) compared with THA patients.
Discussion: Pain medication was significantly overprescribed by more than 34% in TKA and 140% in THA. Prescribing practices of narcotic pain medications following total joint arthroplasty result in significantly excess amount of opioids available for potential abuse.
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http://dx.doi.org/10.5435/JAAOS-D-18-00404 | DOI Listing |
Cureus
September 2025
General Surgery, Norfolk and Norwich University Hospital, Norwich, GBR.
Enhanced recovery after surgery (ERAS) protocols are increasingly used in total hip and knee arthroplasty to improve outcomes, reduce complications, and shorten hospital stays. This involves a multidisciplinary, evidence-based approach covering the preoperative to postoperative period. This review explores the current literature on ERAS implementation in elective total hip arthroplasty (THA) and total knee arthroplasty (TKA), focusing on clinical outcomes such as length of stay (LOS), opioid use, complications/readmissions, and other key components such as anesthetic standardization, use of opioid-sparing analgesia agents, early mobilization, and patient satisfaction.
View Article and Find Full Text PDFJ Arthroplasty
September 2025
Implant Research Core, School of Biomedical Engineering, Science, and Health Systems, Drexel University, Philadelphia, PA, USA.
Background: In a subset of total hip arthroplasty (THA) patients, investigators associate metal release with biological complications. Comparatively, metal release in the knee is less understood. In this study, we systematically reviewed total knee arthroplasty (TKA) metal release studies.
View Article and Find Full Text PDFJ Bone Joint Surg Am
September 2025
Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
Background: Although patients often aim to lose weight after total hip arthroplasty (THA) or total knee arthroplasty (TKA), long-term changes in body mass index (BMI) are unknown. We analyzed BMI at 2, 5, and 10 years after primary THA and TKA and determined predictors of BMI change.
Methods: We identified patients who underwent primary THA or TKA for osteoarthritis between 2001 and 2011 and had a BMI at surgery and at 2, 5, and 10 years postoperatively.
PLoS One
September 2025
Bone Joint and Related Tissues Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: Surgical site infection (SSI) is associated with a significant burden in orthopedic surgeries, leading to increased morbidity, prolonged hospital stays, and higher healthcare costs. Despite the widespread use of prophylactic antibiotics to reduce the risk of infection, the optimal duration for antibiotic administration remains controversial. Newer studies reported controversial results compared to existing guidelines; therefore, we aimed to compare the efficacy and post-operative complications of short-term (<24 hours) and extended oral antibiotics in reducing infection rates following orthopedic surgeries.
View Article and Find Full Text PDFMedicine (Baltimore)
August 2025
Department of Orthopaedics, People's Hospital of Chongqing Hechuan, Chongqing, Chongqing, China.
Background: Artificial intelligence (AI) has significantly advanced the field of joint arthroplasty by transforming key aspects such as surgical planning, implant design, and postoperative management. Despite their growing importance, research trends and priorities in AI applications for joint arthroplasty remain underexplored. This study employed bibliometric analysis to elucidate the main research focus areas and global trends in AI and arthroplasty from 2001 to 2025.
View Article and Find Full Text PDF