98%
921
2 minutes
20
Background: Fostering a culture of safety is an essential step in ensuring patient safety and quality in primary care. We aimed to evaluate the effectiveness of an educational intervention to improve the safety culture in the family and community medicine teaching units in an Atlantic European Region.
Methods: Randomized study conducted in family and community medicine teaching units in Galicia (Spain). Participants were all fourth-year residents and their tutors (N = 138). Those who agreed to participate were randomized into one of two groups (27 tutors/26 residents in the intervention group, 23 tutors/ 23 residents in the control one).All were sent the Survey on Patient Safety Culture. After that, the intervention group received specific training in safety; they also recorded incidents over 15 days, documented them following a structured approach, and had feedback on their performance. The control group did not receive any action. All participants completed the same survey four months later. Outcome measures were the changes in safety culture as quantified by the results variables of the Survey: Patient Safety Grade and Number of events reported. We conducted bivariate and adjusted analyses for the outcome measures. To explore the influence of participants' demographic characteristics and their evaluation of the 12 dimensions of the safety culture, we fitted a multivariate model for each outcome.
Results: Trial followed published protocol. There were 19 drop outs. The groups were comparable in outcome and independent variables at start. The experiment did not have any effect on Patient safety grade (- 0.040) in bivariate analysis. The odds of reporting one to two events increased by 1.14 (0.39-3.35), and by 13.75 (2.41-354.37) the odds of reporting 3 or more events. Different dimensions had significant independent effects on each outcome variable.
Conclusion: A educational intervention in family and community medicine teaching units may improve the incidents reported. The associations observed among organizational dimensions and outcomes evidence the complexity of patient safety culture measurement and, also, show the paths for improvement. In the future, it would be worthwhile to replicate this study in teaching units from different settings and with different health professionals engaged.
Trial Registration: It was retrospectively registered with ( ISRCTN41911128 , 31/12/2010).
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337818 | PMC |
http://dx.doi.org/10.1186/s12875-018-0901-8 | DOI Listing |
Obesity (Silver Spring)
September 2025
Eli Lilly and Company, Indianapolis, Indiana, USA.
Objective: SURMOUNT-MAINTAIN aims to evaluate the efficacy and safety of reducing the tirzepatide dose and/or continuing the maximum tolerated dose (MTD) versus placebo in maintaining body weight (BW) reduction achieved with tirzepatide MTD.
Methods: This Phase 3b, multicenter, randomized, parallel-arm, double-blinded, placebo-controlled, 52-week clinical trial is in progress comparing treatment with once weekly tirzepatide (5 mg and/or MTD of 15 mg or 10 mg) versus placebo in achieving BW reduction maintenance from the initial 60-week open-label weight-loss period on tirzepatide MTD, in adults with obesity (BMI ≥ 30 kg/m or ≥ 27 kg/m with ≥ 1 obesity-related comorbidity, excluding type 2 diabetes). The primary endpoint is percent maintenance of BW reduction achieved during the weight-loss period at Week 112 among those who reached a BW plateau (i.
Objective: To quantify C-arm-registered radiation exposure during ultrasound- and fluoroscopy-guided spinal interventional pain management in dogs, and to measure operator-based radiation levels to identify discrepancies between delivered and received dose.
Study Design: A retrospective observational study.
Animals: A total of 82 canine spinal interventional pain management procedures performed at a single referral institution.
Pestic Biochem Physiol
November 2025
Key Laboratory of Agri-Food Safety of Anhui Province, Anhui Agricultural University, Hefei 230036, China. Electronic address:
The Asian Corn Borer (ACB), Ostrinia furnacalis (Guenée) is a devastating pest of maize, causing significant yield and economic losses in Asia. GABA receptor inhibitors have served as effective tools for controlling ACB larvae over the past several decades. However, the toxicity levels and pharmacological properties of two insecticides, fluxametamide and fipronil against the ACB are still unclear.
View Article and Find Full Text PDFPestic Biochem Physiol
November 2025
Departamento de Entomologia, Universidade Federal de Viçosa, 36570-900 Viçosa, MG, Brazil. Electronic address:
Managing Euschistus heros is increasingly challenging due to insecticide resistance, limited available molecules, and environmental and health concerns. Here, we synthesized and evaluated mucochloric acid derivatives as alternative tools for controlling this pest. We assessed the selectivity of these molecules toward the pollinators bees Apis mellifera and Partamona helleri and conducted in silico predictions for the interactions of these molecules with receptors for γ-aminobutyric acid (GABARs) and nicotinic acetylcholine receptors (nAChRs), and the enzyme acetylcholinesterases (AChE) of E.
View Article and Find Full Text PDFPestic Biochem Physiol
November 2025
State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China; Hubei Hongshan Laboratory, Wuhan, Hubei, China; Hubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory, College of Plant, Science and Technology, Huazhong Agricultural
Galectins are a family of carbohydrate-binding proteins known to maintain intestinal microbiota homeostasis. Emerging evidence suggests that the bacterial symbiont plays a role in modulating insecticide resistance in insect. However, whether galectins influence insecticide susceptibility through microbiota regulation remains unclear.
View Article and Find Full Text PDF