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Background And Purpose: Previous literature suggests that reductions in appendicular skeletal mass (ASM) may have a greater detrimental effect than total lean body mass regarding the onset and progression of sarcopenia. Unfortunately, limited access to equipment that accurately determines ASM often leads to many individuals remaining undiagnosed and experiencing functional decline. Therefore, the purpose of this investigation was to determine the ability of functional and neuromuscular measures to identify ASM in older women.
Methods: Forty-one (sarcopenic n = 15) older women underwent body composition analysis via dual-energy X-ray absorptiometry (DXA) and performed the following measures: bench press (BP) 1-repetition maximum strength (1RM), vertical jump height and power, handgrip strength, Timed Up and Go test, Berg Balance Scale testing, and bench press power testing at 20%, 40%, and 60% 1RM.
Results And Discussion: Regression analyses revealed 3 significant models accounting for 93.8%, 91.1%, and 86.4% of the variance in DXA-derived ASM. Paired-samples t tests revealed no significant differences between model-derived and DXA-derived ASM for each model, and each model was significantly correlated to DXA-derived ASM (P < .001). In addition, each model revealed a strong ability to appropriately classify sarcopenia status, with the area under the curve values ranging from 0.86 to 0.93. The present data indicate that ASM can be determined with high precision by measuring outcome variables such as jump power, body weight, and grip strength in older women.
Conclusions: Therefore, the present models could be used to identify, screen, or classify older women as sarcopenic, ultimately allowing the implementation of interventions aimed at decreasing the difficulty of activities of daily living and increasing quality of life.
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http://dx.doi.org/10.1519/JPT.0000000000000219 | DOI Listing |
JAMA Netw Open
September 2025
Centre de recherche intégrée pour un système apprenant en santé et services sociaux, Centre intégré de santé et de services sociaux de Chaudière-Appalaches, Lévis, Québec, Canada.
Importance: Caregivers of community-dwelling older adults play a protective role in emergency department (ED) care transitions. When the demands of caregiving result in caregiver burden, ED returns can ensue.
Objective: To develop models describing whether caregiver burden is associated with ED revisits and hospital admissions up to 30 days after discharge from an initial ED visit.
J Neurooncol
September 2025
Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada.
Purpose: Breast cancer (BC) is the most frequent cancer among women and the second leading cause of central nervous system (CNS) metastases. While the epidemiology of CNS metastases from BC has been well described, little is known about the treatment patterns and outcomes of young women < 40 years of age with BC that is metastatic to the CNS.
Methods: In this retrospective analysis, we identified patients with metastatic breast cancer (MBC) to the CNS who were treated at the Sunnybrook Odette Cancer Center, Toronto, Canada between 2008 and 2018.
Breast Cancer Res Treat
September 2025
Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA.
Purpose: Black women with hormone receptor-positive (HR +) breast cancer are twice as likely as White women to have weakly HR + tumors (1-10% positive cells). Patients with weakly HR + tumors are less frequently prescribed ET and have 60% higher mortality than strongly HR + tumors (> 10% positive cells). We evaluated factors associated with ET prescription and self-reported use among Black women with HR + breast cancer.
View Article and Find Full Text PDFClimacteric
September 2025
Gynecology Discipline, Obstetrics and Gynecology Department, University of São Paulo School of Medicine, São Paulo, Brazil.
Objective: Social media is an increasingly relevant tool for health education, enabling information exchange, promoting autonomy and supporting informed decision-making. This study introduces Menopausando, a predominantly Portuguese-language digital platform designed to support women during menopausal transition and postmenopause.
Method: This cross-sectional study has been carried out in the Gynecology Discipline, São Paulo University, Brazil, since 2019.
This study examined sociodemographic and health-related determinants of self-reported unmet health service needs to better understand the factors contributing to inequities among adults aged 50 and older during the COVID-19 pandemic in Latvia. Data from the longitudinal SHARE study-Corona Surveys 1 and 2, and Wave 8-were analysed using logistic regression. A total of 647 cases from Latvia (62.
View Article and Find Full Text PDF