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Objective: The primary objective of this study was to evaluate the utility, clinical impact, and work flow of a new trauma hybrid operating theater.
Summary Background Data: The potential utility and clinical benefit of hybrid operating theaters are increasingly postulated. Unfortunately, the clinical outcomes and efficiencies of these environments remain unclear.
Methods: All severely injured patients who were transferred to the hybrid suite for emergent intervention between 2013 and 2017 were compared to consecutive prehybrid patients. Standard statistical methodology was employed (P < 0.05 = significant).
Results: One hundred sixty-nine patients with severe injuries (mean ISS = 23; hemodynamic instability = 70%; hospital/ICU stay = 12 d; mortality = 14%) were transferred urgently to the hybrid suite. Most were young (38 yrs) males (84%) with blunt injuries (51%). Combined hybrid trauma procedures occurred in 18% of cases (surgery (82%) and angiography (11%) alone). Procedures within the hybrid suite included: laparotomy (57%), extremity (14%), thoracotomy/sternotomy (12%), angioembolization of the spleen/pelvis/liver/other (9%), neck (9%), craniotomy (4%), and aortic endostenting (6%). Compared with historical controls, use of the hybrid suite resulted in shorter arrival to intervention and total procedure times (P < 0.05). A clear benefit for survival was evident (42% vs. 22%).
Conclusions: Availability of a hybrid environment for severely injured patients reduces time to intervention, total procedural duration, blood product transfusion and salvages a small subset of patients who would not otherwise survive. The cost associated with a hybrid suite remains prohibitive for many centers.
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http://dx.doi.org/10.1097/SLA.0000000000003175 | DOI Listing |
RSC Adv
September 2025
Department of Chemical Engineering, Jashore University of Science and Technology Jashore 7408 Bangladesh
Bacterial detection is crucial for accurate clinical diagnostics and effective environmental monitoring. Particularly, , a pathogenic bacterium, can cause a wide range of infections, including meningitis, bloodstream infections, pneumonia, urinary tract infections, and wound or surgical site infections. Herein, a polypyrrole (PPy) functionalized TiCT -tin dioxide nanoparticle (SnO NPs) nanocomposite-based hybrid capacitive electrode for the electrochemical detection of ATCC 700603 is developed.
View Article and Find Full Text PDFJ Healthc Leadersh
August 2025
Department of Medical Equipment Technology, College of Applied Medical Science, Majmaah University, Majmaah, 11952, Saudi Arabia.
Introduction: Clinical Engineering Departments (CEDs) face growing challenges in managing rapidly evolving medical technologies and increasing equipment inventories under constrained budgets and limited human resources. These pressures often result in strained staffing capacity and imbalanced workload distribution. This study aimed to develop and validate a metrics-driven hybrid staffing model to optimize workforce allocation and improve workload efficiency across National Guard Health Affairs (NGHA) hospitals in Saudi Arabia.
View Article and Find Full Text PDFSci Rep
September 2025
Department of Mechanical Engineering, College of Engineering, University of Ha'il, Ha'il City, 81451, Saudi Arabia.
Accurate assessment of intracranial aneurysm rupture risk, particularly in Middle Cerebral Artery (MCA) aneurysms, relies on a detailed understanding of patient-specific hemodynamic behavior. In this study, we present an integrated framework that combines Computational Fluid Dynamics (CFD) with Proper Orthogonal Decomposition (POD) and machine learning (ML) to efficiently model pulsatile blood flow using a Casson non-Newtonian fluid model, without incorporating fluid-structure interaction (FSI). Patient-specific vascular geometries were reconstructed from DICOM imaging data and simulated using ANSYS Fluent to capture key hemodynamic factors, including velocity components, pressure, wall shear stress (WSS), and oscillatory shear index (OSI).
View Article and Find Full Text PDFArXiv
August 2025
Department of Genetics, Yale University, New Haven, CT 06510, USA.
A key output of the NIH-Common Fund 4D Nucleome (4DN) project is the open publication of datasets related to the structure of the human cell nucleus and the genome. Recent years have seen a rapid expansion of multiplexed Fluorescence In Situ Hybridization (FISH) or FISH-omics methods, which quantify the spatial organization of chromatin in single cells, sometimes together with RNA and protein measurements, and provide an expanded understanding of how 3D higher-order chromosome structure relates to transcriptional activity and cell development in both health and disease. Despite this progress, results from Chromatin Tracing FISH-omics experiments are difficult to share, reuse, and subject to third-party downstream analysis due to the lack of standard specifications for data exchange.
View Article and Find Full Text PDFSci Rep
September 2025
Centre for Smart Grid Technologies, Vellore Institute of Technology, Chennai, India.
With a rising global population and vehicle usage, electric vehicles (EVs) have emerged as a sustainable solution for carbon neutrality. The paper's main objective is to test the performance of the optimized coil design for the Inductive power transfer (IPT) prototype designed for 48 V light EV (LEV) applications operating at 86 kHz. The coils are optimized for objectives such as compactness and power transfer efficiency, using a hybrid multi-objective optimization algorithm combining Taylor-series tuning and Dove Swarm (DSO) optimization.
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