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Article Abstract
The binding properties of quercetin toward chloride anions were investigated by means of ¹H-NMR, C-NMR, and electrospray ionization mass spectrometry (ESI-MS) measurements, as well as computational calculations. The results indicate that quercetin behaves primarily as a ditopic receptor with the binding site of the B ring that exhibits stronger chloride affinity compared to the A ring. However, these sites are stronger receptors than those of catechol and resorcinol because of their conjugation with the carbonyl group located on the C ring. The 1:1 and 1:2 complexation of this flavonoid with Cl was also supported by ESI mass spectrometry.
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| http://dx.doi.org/10.3390/molecules23123366 | DOI Listing |
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