A Path(way) to Keeping Your Synapses on an Even Keel.

Neuron

Pathology and Laboratory Medicine, Weill Cornell Medicine, New York City, NY, USA.

Published: December 2018


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Article Abstract

In this issue of Neuron, Harris et al. (2018) show that a signal transduction pathway normally exploited by the innate immune system in recognizing foreign agents plays a critical role in controlling a synapse's ability to maintain stability in the efficacy of synaptic transmission over both rapid and prolonged timescales.

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http://dx.doi.org/10.1016/j.neuron.2018.11.033DOI Listing

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