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Background: Ulnar collateral ligament (UCL) injuries represent one of the most common impairments to the throwing arm of professional pitchers. Return to play and postoperative performance metrics have been studied extensively, but pitch selection before and after surgery has not been evaluated.
Purpose/hypothesis: This study aimed to characterize the effects of UCL reconstruction on pitch selection in Major League Baseball (MLB) pitchers. We hypothesized that pitchers will throw fewer fastballs and a greater percentage of off-speed pitches after undergoing UCL reconstruction.
Study Design: Retrospective cohort study; Level of evidence, 3.
Methods: Using publicly available data, we evaluated MLB pitchers who underwent UCL reconstruction between 2003 and 2014. Pitching data were collected for the 2 seasons before UCL reconstruction as well as the first 2 seasons after reconstruction; the data consisted of the total number of pitches thrown and the percentage of fastballs, curveballs, changeups, and sliders. Repeated-measures analysis of variance was used with post hoc least significant difference pairwise tests to evaluate for statistical significance at < .05.
Results: Overall, 87 pitchers (mean age, 28.2 ± 3.5 years) met all inclusion and exclusion criteria. There was a statistically significant difference in the total number of pitches thrown before and after surgery ( < .01) as well as in the percentage of fastballs thrown before and after surgery ( = .02). There was also a statistically significant increase in the use of curveballs between 1 and 2 years postoperatively (7.5% and 8.8%, respectively; = .01). No other findings were statistically significant.
Conclusion: Pitchers who underwent UCL reconstruction were shown to have a statistically significant decline in the percentage of fastballs thrown postoperatively as compared with before injury, with a compensatory trend toward an increased use of curveballs and sliders.
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http://dx.doi.org/10.1177/2325967118810003 | DOI Listing |
Aesthetic Plast Surg
September 2025
Faculty of Medicine and Health Sciences (FMHS), Plastic, Aesthetic and Reconstructive Surgery Unit, Universiti Malaysia Sabah, 88400, Kota Kinabalu, Sabah, Malaysia.
Introduction: Unilateral cleft lip nasal (UCL/N) deformity severity presents complex anatomical challenges, with surgical outcomes influenced by preoperative status. Existing classification systems for UCL/N lack standardization, relying on subjective clinical assessments or isolated anthropometric measures that fails to assess anatomical deformity comprehensively. This limits their utility in objectively stratifying deformity severity and justifying postoperative outcomes.
View Article and Find Full Text PDFJ Plast Reconstr Aesthet Surg
August 2025
University College London, London, United Kingdom; Royal Free London NHS Foundation Trust, London, United Kingdom.
Background: In the deep inferior epigastric perforator (DIEP) flap breast reconstruction, fat necrosis is a common and distressing complication for patients. While venous outflow augmentation using the superficial inferior epigastric vein (SIEV) has been suggested to improve some perfusion-related outcomes, its effect on fat necrosis remains insufficiently substantiated.
Methods: A retrospective review was conducted of unilateral, unipedicled DIEP flap breast reconstructions performed between 2012 and 2023 at a tertiary centre in London, United Kingdom.
Neuroimage
August 2025
Movement & Neuroscience, Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark. Electronic address:
Learning a new motor skill relies on functional reorganization of the human central nervous system (CNS). Plasticity may shape the transmission and communication between cortical regions and between cortical and spinal networks involved in sensorimotor control, but little is known about the influence of age on these adaptations. In a series of experiments, we investigated whether changes in cortical and corticospinal functional connectivity following motor practice differ among individuals at different stages of development (age range 8-30 years old).
View Article and Find Full Text PDFProc IEEE Comput Soc Conf Comput Vis Pattern Recognit
June 2025
Data-driven machine learning has made significant strides in medical image analysis. However, most existing methods are tailored to specific modalities and assume a particular resolution (often isotropic). This limits their generalizability in clinical settings, where variations in scan appearance arise from differences in sequence parameters, resolution, and orientation.
View Article and Find Full Text PDFNature
August 2025
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Both single nucleotide variants (SNVs) and somatic copy number alterations (SCNAs) accumulate in cancer cells during tumour development, fuelling clonal evolution. However, accurate estimation of clone-specific copy numbers from bulk DNA-sequencing data is challenging. Here we present allele-specific phylogenetic analysis of copy number alterations (ALPACA), a method to infer SNV and SCNA coevolution by leveraging phylogenetic trees reconstructed from multi-sample bulk tumour sequencing data using SNV frequencies.
View Article and Find Full Text PDF