Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Objective: To document the demographic risk factors of workers reported to have silicosis in the UK.
Methods: All cases of silicosis reported to the Surveillance of Work-related and Occupational Respiratory Disease (SWORD) scheme between January 1996 and December 2017 were classified into one of eight industry categories, and one of five age groups. In addition, to investigate whether there had been any temporal change, mean age and range at diagnosis was plotted for each year. From 2006, data were also available relating to the date of onset of symptoms, allowing a comparison between workers with and without respiratory symptoms.
Results: For the period between 1996 and 2017, there were 216 cases of silicosis reported. The mean (range) age of those reported was 61 years (23-89), with the majority (98%) being male. Across all industries, 65% of cases were diagnosed in individuals of working age (<65 for men and <60 for women). Silicosis was reported in young workers across all industry groups, with around one in six of all silicosis cases affecting workers under the age of 46 years. There was no clear trend in age of diagnosis with time. Between 2006 and 2017, 81% of 108 workers with silicosis were reported to be symptomatic.
Conclusions: Silicosis remains an important health problem in the UK affecting workers of all ages across a wide range of industries traditionally associated with silica exposure.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327866 | PMC |
| http://dx.doi.org/10.1136/oemed-2018-105337 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Cellular senescence in cancer: from mechanism paradoxes to precision therapeutics.
Mol Cancer
August 2025
Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, Prince of Wales Hospital, Sir Y.K. Pao Cancer Center, The Chinese University of Hong Kong, Hong Kong, China.
Cellular senescence is a double-edged sword in cancer biology, functioning as both a tumor-suppressive mechanism and a driver of malignancy. Initially, senescence acts as a protective barrier by arresting the proliferation of damaged or oncogene-expressing cells via pathways such as oncogene-induced senescence and the DNA damage response. However, persistent senescence-associated secretory phenotype and metabolic reprogramming in senescent cells create a pro-inflammatory, immunosuppressive tumor microenvironment, fueling cancer progression, therapy resistance, and metastasis.
View Article and Find Full Text PDFA systematic review of incentive schemes and their implications for truck driver safety performance.
J Safety Res
February 2025
Department of Logistics, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa. Electronic address:
Introduction: This systematic review investigates the effects of monetary and non-monetary incentive schemes on the safety performance of truck drivers, a critical concern within the road freight industry.
Method: The review analyzes 18 studies and dissects the impact of compensation levels, compensation methods, and non-monetary benefits on drivers' safety behaviors.
Results: The findings show that, in general, higher levels of compensation, both through selection and incentive effects, enhance safety performance by attracting more skilled drivers and incentivizing adherence to safety protocols.
Trends in occupational respiratory conditions with short latency in the UK.
Occup Med (Lond)
September 2024
Centre for Occupational and Environmental Health, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Background: Occupational short-latency respiratory disease (SLRD; predominantly asthma, rhinitis, hypersensitivity pneumonitis, and occupational infections) prevalence is difficult to determine but certain occupations may be associated with increased susceptibility.
Aims: This study aimed to examine which occupations and industries are currently at high risk for SLRD and determine their respective suspected causal agents.
Methods: SLRD cases reported to the SWORD scheme between 1999 and 2019 were analysed to determine directly standardized rate ratios (SRR) by occupation against the average rate for all other occupations combined.
Trends in work-related respiratory diseases attributed to nickel, chromium and cobalt in the UK: descriptive findings from The Health and Occupation Research (THOR) network 1996-2019.
Occup Environ Med
April 2024
Centre for Occupational and Environmental Health, Division of Population Health, Health Services Research and Primary Care, The University of Manchester Faculty of Biology Medicine and Health, Manchester, UK.
Background: Occupational exposure to metals can be associated with respiratory diseases which can adversely affect the individual's health, finances and employment. Despite this, little is known about the incidence of these respiratory conditions over prolonged periods of time.
Aims: This study aimed to investigate the trends in the incidence of work-related respiratory diseases attributed to nickel, chromium and cobalt in the UK.
MicroRNA-155, a double-blade sword regulator of innate tuberculosis immunity.
Microb Pathog
December 2023
Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, 72388, Saudi Arabia. Electronic address:
Tuberculosis (TB) is a chronic, life-threatening disease caused by unusual facultative intracellular bacteria, Mycobacterium tuberculosis. This bacterium has unique resistance to many antimicrobial agents and has become a major global health concern due to emerging multidrug-resistant strains. Additionally, it has developed multiple schemes to exploit host immune signaling and establish long-term survival within host tissues.
View Article and Find Full Text PDF