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http://dx.doi.org/10.1016/j.jpainsymman.2018.10.490 | DOI Listing |
J Laryngol Otol
September 2025
Department of Otolaryngology, Head and Neck Surgery, University Hospital Galway, Ireland.
Intractable Rare Dis Res
August 2025
Department of Diabetes, Endocrinology and Metabolism, National Center for Global Health and Medicine, Tokyo, Japan.
To review musculoskeletal disabilities and rehabilitation in adults with thalidomide embryopathy (TE), the authors reviewed the literature related to musculoskeletal disability, quality of life (QOL) and rehabilitation intervention in adults with TE, obtained through a PubMed search, and their experience in clinical practice with Japanese individuals. Through literature search, 25 studies were included for this review. Literature search results and the authors' experiences revealed that, in adults with TE, upper limb disabilities included neuropathy, mainly due to carpal tunnel syndrome; finger pain due to tenosynovitis; and symptoms caused by osteoarthritis, mainly in the shoulders.
View Article and Find Full Text PDFAm J Rhinol Allergy
August 2025
Department of Otolaryngology, Head & Neck Surgery, Prince of Wales Hospital, Sydney, NSW, Australia.
BackgroundEndoscopic sphenopalatine artery ligation (ESPAL) is a safe and effective procedure to manage intractable epistaxis. However, in the literature, the peri-operative and patient factors which contribute to surgical success or failure have been poorly defined.ObjectiveThe purpose of this study was to identify the patient, disease and surgical factors which influence the effectiveness of ESPAL in the management of intractable epistaxis.
View Article and Find Full Text PDFNeurotoxicology
September 2025
Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Ansan Hospital, Republic of Korea; Laboratory of Otorhinolaryngology-Head & Neck Surgery, Graduate School of Medicine, Korea University. Republic of Korea; Biomedical Research Center, Korea University Coll
Osthole, a coumarin derivative with potent antioxidant and anti-inflammatory properties, has demonstrated promising therapeutic potential in protecting against ototoxicity. This study investigated the protective effects of osthole through both in vitro and in vivo experimental models. A high-content screening of 1505 natural compounds in HEI-OC1 cells identified osthole as the most effective compound in alleviating gentamicin-induced cellular damage.
View Article and Find Full Text PDFCureus
July 2025
Internal Medicine, AdventHealth Orlando, Orlando, USA.
We report a case of a 61-year-old immunosuppressed man with rheumatoid arthritis on etanercept and past intravenous drug use who presented with intractable hiccups, an unreported feature of cervical necrotizing fasciitis (CNF). He was initially diagnosed with a viral syndrome, but later developed severe sepsis with neck swelling, dysphagia, and ligneous induration. The absence of skin changes, probably secondary to etanercept-induced immunosuppression, hindered diagnosis.
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