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Many Service members and Veterans with lower-limb amputations have the potential for high function and the desire to resume physically demanding occupations that require them to carry heavy loads (e.g., military service, firefighters, farmers, ranchers, construction workers). However, it is currently unclear which prosthetic feet best accommodate heavy load carriage while also providing good overall function and mobility during unweighted activities. The main objective of this study was to investigate the ability of currently available prosthetic ankle-foot systems to accommodate weighted walking by examining the mechanical characteristics (i.e., forefoot stiffness) and dynamic function (i.e., rocker radius, effective foot length ratio, and late-stance energy return) of prosthetic feet designed for high activity users. Load versus deflection curves were obtained for nine prosthetic ankle-foot systems using a servohydraulic test frame and load cell. Effective roll-over shape characteristics and late-stance energy return measures were then obtained using quantitative gait analysis for three users with unilateral, transtibial amputation. Results from mechanical and dynamic testing showed that although forefoot stiffness varied across the nine feet investigated in this study, changes measured in roll-over shape radius and effective foot length ratio were relatively small in response to weighted walking. At the same time, prosthetic feet with more compliant forefoot keel structures appeared to provide more late-stance energy return compared to feet with stiffer forefoot keel structures. These results suggest that prosthetic ankle-foot systems with compliant forefoot keel structures may better accommodate weighted walking by reducing the metabolic cost of physically demanding activities. However, to more fully understand the biomechanical and functional implications of these results, other factors, such as the residual-limb strength of the user and the overall stiffness profile of the prosthetic foot, should also be considered.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135372 | PMC |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0202884 | PLOS |
Gait Posture
August 2025
Department of Medical and Robotic Engineering Design, Faculty of Advanced Engineering, Tokyo University of Science, Tokyo, Japan. Electronic address:
Background: Individuals with unilateral transfemoral amputation (uTFA) are at increased risk of secondary musculoskeletal conditions due to excessive loading on the intact limb during functional activities. However, limited evidence exists regarding weight-bearing asymmetry during quiet standing in this population.
Research Question: Is weight-bearing asymmetry during quiet standing associated with demographic characteristics in physically active individuals with uTFA?
Methods: Thirty-four individuals with uTFA were recruited.
BMC Musculoskelet Disord
September 2025
Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
Introduction: 3D-printing is an emerging technology that is used in the manufacturing of orthotic devices. 3D-printing has many advantages such as improved fit, comfort, effectiveness, and patient satisfaction. While some challenges like durability and material selection remain, the aim of this systematic review is to provide a comprehensive evaluation of the clinical outcomes of 3D-printed orthoses.
View Article and Find Full Text PDFGait Posture
August 2025
Clinical Research and Services, Research Biomechanics, Ottobock SE & Co. KGaA, Göttingen, Germany; HAWK University of Applied Sciences and Arts, Göttingen, Germany. Electronic address:
Background: Prosthetic fittings for persons with a transfemoral amputation should provide adequate ground clearance (GC) during prosthetic side swing to minimize the risk of stumbling or falling. Insufficient ground clearance often leads to compensatory movements that consequently influence gait biomechanics negatively.
Research Question: How do different prosthetic components and alignment of a transfemoral prosthesis affect prosthetic side GC and compensatory strategies during level walking?
Methods: Eight persons with transfemoral amputation were enrolled.
Cochrane Database Syst Rev
August 2025
Department of Research, Sint Maartenskliniek, Nijmegen, Netherlands.
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the effects of different prosthetic ankle-foot mechanisms for improving health-related quality of life, functional, and biomechanical outcomes in adult prosthesis users after major lower limb amputation.
View Article and Find Full Text PDFIEEE Trans Neural Syst Rehabil Eng
September 2025
Hip disarticulation (HD) amputees face mobility challenges due to the loss of hip, knee, and ankle joints. Current hip-knee-ankle-foot (HKAF) prostheses are entirely passive and require excessive compensatory movements to operate, leading to fatigue and long-term complications. Seeking to address these limitations, this study developed a HD user-centric, walking speed adaptable control strategy paired with a hip-motorized HKAF to emulate gait characteristics of transfemoral amputees.
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