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Editorial Commentary: Current evidence does not support routine augmentation of anterior cruciate ligament reconstruction with platelet rich plasma, but the pursuit of biologic enhancements to improve ACL surgical outcomes should continue.
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Southern California Orthopedic Institute, Van Nuys, CA. Electronic address:
Platelet Rich Plasma (PRP) has been utilized to augment ACL surgery, with studies reaching conflicting conclusions as to the extent of beneficial effects. While the majority of ACL surgeries I have performed have not been augmented, I have utilized PRP (and bone marrow concentrate) enough to conclude that my personal experience matches literature finding no significant difference in outcomes, and, at present does not support routine augmentation of ACL reconstruction (ACLR) with PRP. Instead, I believe the "crimson duvet" effect of reaming tunnels is a key source of cells and signals that promote healing and initiate graft incorporation.
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Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Blood culture contamination (BCC) is a major healthcare challenge with no standardized process to monitor and report rates by individual healthcare facilities in the United States. A new study by V. Fabre, Y.
View Article and Find Full Text PDFUsing Machine Learning to Predict Advanced-Stage Progression of Intermediate-Stage Hepatocellular Carcinoma after Transarterial Chemoembolization.
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Department of Radiation Oncology, Cancer Center, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan Road, Guangzhou, China 510080.
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View Article and Find Full Text PDFArterial Ischemic Stroke in Children: Navigating Diagnostic and Management Pathways.
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Division of Neuroradiology, Department of Diagnostic and Interventional Radiology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Pediatric stroke is garnering increased attention due to its rising incidence and significant impact on affected children, families, and the health care system. Arterial ischemic stroke (AIS) is a major subtype of pediatric stroke and often results from arterial occlusion. Diagnosis and treatment of acute ischemic stroke in children pose unique challenges, primarily because of nonspecific symptoms, lack of pediatric-focused imaging protocols, distinct causes (compared with in adults), and the large number of stroke mimics.
View Article and Find Full Text PDFCall for founding members of the European Organization For University Physical and Rehabilitation Medicine (UniPRM).
J Rehabil Med
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Department of Mental and Physical Health and Preventive Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Rehabilitation is increasingly recognized as a key component of health systems worldwide. To meet the growing demand for rehabilitation services, it is essential to strengthen academic capacity in Physical and Rehabilitation Medicine within universities. Academic structures are critical for training future physicians and professionals, and for advancing research and innovation in rehabilitation.
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