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http://dx.doi.org/10.4103/ijem.IJEM_119_18 | DOI Listing |
Int J Pharm X
June 2025
Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325015, China.
Ultra-sensitive pH-responsive drug delivery system designed to operate within the slightly acidic microenvironment of tumors are highly desired for hydrogel applications in cancer therapy. In this study, 4-Formylbenzoic acid modified polyvinyl alcohol (PVA-FBA, PF) was synthesized and utilized as a carrier for encapsulating the anticancer drug Doxorubicin (Dox). This was subsequently crosslinked with polyethylenimine (PEI) via benzoic-imine bond to form drug-loaded PVA-FBA/PEI hydrogel (D-PFP).
View Article and Find Full Text PDFJB JS Open Access
September 2025
Department of Orthopaedic Surgery, Mass General Brigham, Harvard Medical School, Boston, Massachusetts.
Background: It is unclear whether the current North Atlantic Treaty Organization (NATO) trauma system will be effective in the setting of Large-Scale Combat Operations (LSCO). We sought to model the efficacy of the NATO trauma system in the setting of LSCO. We also intended to model novel scenarios that could better adapt the current system to LSCO.
View Article and Find Full Text PDFVet World
July 2025
Department of Plant Protection, Faculty of Agriculture, Universitas Sriwijaya, 30662 Indralaya, Indonesia.
Background And Aim: Zoonotic malaria remains a significant public health concern in Southeast Asia. The potential role of cattle as reservoirs for spp. in Indonesia has not been fully elucidated, despite increasing recognition of animal reservoirs in malaria transmission dynamics.
View Article and Find Full Text PDFMol Pharm
September 2025
Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an 710061, PR China.
Acute kidney injury (AKI) is a common clinical syndrome characterized by abnormal renal function and structure. Microcirculatory perfusion disorders and inflammatory responses are critical pathophysiologies of AKI. Recently, ultrasound molecular imaging has been considered a valuable tool for preclinical and clinical diagnostics that can sensitively target histological structures of interest, particularly in evaluating renal microcirculation.
View Article and Find Full Text PDFJ Phys Chem A
September 2025
MOE Key Laboratory for Non-Equilibrium Synthesis and Modulation of Condensed Matter, School of Physics, Xi'an Jiaotong University, Xi'an 710049, Shaanxi, P. R. China.
Understanding the active sites of copper (Cu)-based catalysts toward CO is a prerequisite for improving their rational design. The reactivity of copper oxide cluster anions CuO ( = 3-9) and bare copper cluster anions Cu toward CO has been investigated at room temperature by employing mass spectrometry combined with density functional theory (DFT) calculations. Only adsorption products are observed for the reaction of CuO with CO.
View Article and Find Full Text PDF