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Almost four decades ago, Gacs, Kurdyumov, and Levin introduced three different cellular automata to investigate whether one-dimensional nonequilibrium interacting particle systems are capable of displaying phase transitions, and, as a byproduct, they introduced the density classification problem (the ability to classify arrays of symbols according to their initial density) in the cellular automata literature. Their model II became a well-known model in theoretical computer science and statistical mechanics. The other two models, however, did not receive much attention. Here we characterize the density classification performance of Gacs, Kurdyumov, and Levin's model IV, a four-state cellular automaton with three absorbing states-only two of which are attractive-by numerical simulations. We show that model IV compares well with its sibling model II in the density classification task: the additional states slow down the convergence to the majority state but confer a slight advantage in classification performance. We also show that, unexpectedly, initial states diluted in one of the nonclassifiable states are more easily classified. The performance of model IV under the influence of noise was also investigated, and we found signs of an ergodic-nonergodic phase transition at some small finite positive level of noise, although the evidence is not entirely conclusive. We set an upper bound on the critical point for the transition, if any.
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http://dx.doi.org/10.1103/PhysRevE.98.012135 | DOI Listing |
J Am Heart Assoc
September 2025
Division of Preventive Medicine Brigham and Women's Hospital, Harvard Medical School Boston MA USA.
Background: Traditional cardiovascular risk assessment entails investigator-defined exposure levels and individual risk markers in multivariable analysis. We sought to determine whether an alternative unbiased learning analysis might provide further insights into vascular risk.
Methods: We conducted an unsupervised learning (k-means cluster) analysis in the Women's Health Study (N=26 443) using baseline levels of triglycerides, high-sensitivity C-reactive protein, and low-density lipoprotein cholesterol to form novel exposures.
J Phys Chem B
September 2025
Department of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey 08544, United States.
Understanding and predicting the phase behavior of intrinsically disordered proteins (IDPs) is of significant interest due to their role in many biological processes. However, effectively characterizing phase behavior and its complex dependence on protein primary sequence remains challenging. In this study, we evaluate the efficacy of several simple computational metrics to quantify the propensity of single-component IDP solutions to phase separate; specific metrics considered include the single-chain radius of gyration, the second virial coefficient, and a newly proposed quantity termed the expenditure density.
View Article and Find Full Text PDFTraffic Inj Prev
September 2025
Department of Civil Engineering, Sardar Vallabhbhai National Institute of Technology, Surat, India.
Objective: This study aimed to identify dynamic spatiotemporal traffic factors influencing conflict risk levels on National Highways under heterogeneous traffic conditions in India. The research addresses gaps by capturing vehicle interactions using high-resolution UAV-based trajectory data and proposes a novel two-stage methodology for real-time conflict risk evaluation, moving beyond traditional binary risk classifications to a four-level framework (High, Moderate, Low, No-Risk).
Methods: Over 40,000 conflict risk sequences were classified into four severity levels using the Modified Time-to-Collision (MTTC) surrogate safety measure.
Understanding the transmission routes of high-pathogenicity avian influenza (HPAI) is crucial for developing effective control measures to prevent its spread. In this context, windborne transmission, the idea that the virus could travel through the air over considerable distances, is a contentious concept, and documented cases have been rare. Here, though, we provide genetic evidence supporting the feasibility of windborne transmission.
View Article and Find Full Text PDFJ Imaging Inform Med
September 2025
Sao Paulo State University (UNESP), Rubião Jr, Botucatu, São Paulo, SP, 18618-687, Brazil.
Breast cancer is the leading cause of cancer-related deaths among women worldwide. Early detection through mammography significantly improves outcomes, with breast density acting as both a risk factor and a key interpretive feature. Although the Breast Imaging Reporting and Data System (BI-RADS) provides standardized density categories, assessments are often subjective and variable.
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