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The complex nature of self-disclosure poses challenges for genetic counselors in clinical practice. We examined the impact of genetic counselor self-disclosure on observer perceptions of the counselor. In an online analog study, 123 participants watched a 3-minute video of a simulated genetic counseling session. For half the participants, the video showed the counselor disclosing that she had a family medical history similar to the patient (direct personal disclosure). For half the participants, the counselor revealed her experience with other patients (direct professional disclosure). Half the participants in each video condition read that the patient had discovered personal information about the counselor during a pre-session web search (indirect personal disclosure); half read that the patient learned of the counselor's FAQ webpage for prospective patients (indirect professional disclosure). Participants in the direct personal disclosure conditions gave higher ratings to the counseling relationship on an abbreviated version of the Barrett-Lennard Relationship Inventory and rated themselves more likely to see the counselor compared to those in the direct professional disclosure conditions. The content of the indirect disclosure conditions (personal or professional) had no effect. Brief, direct, verbal disclosure of session-relevant personal information by a genetic counselor appears to enhance the counselor-patient relationship and increase the likelihood of patients returning to the counselor.
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http://dx.doi.org/10.1007/s10897-018-0283-z | DOI Listing |
Front Genet
August 2025
Department of Medical Genetics, Jiangxi Maternal and Child Health Hospital, Nanchang, China.
Objective: The aim of this study was to determine the diagnostic value of prenatal chromosomal microarray analysis (CMA) for fetuses at high risk for various conditions on chromosomal abnormalities.
Methods: In the study, 8,560 clinical samples were collected from pregnant women between February 2018 and June 2022, including 75 villus, 7,642 amniotic fluid, and 843 umbilical cord blood samples. All samples were screening for chromosomal abnormalities using both CMA and karyotyping.
Front Genet
August 2025
Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Background And Objective: Parental chromosomal structural variations (SVs) represent a primary genetic factor contributing to recurrent spontaneous abortion (RSA). Individuals carrying SVs with complex chromosomal rearrangements (CCRs) typically exhibit a normal phenotype but are at an increased risk of miscarriage. Current standard clinical detection methods are insufficient for the identification and interpretation of all SV types, particularly complex and occult SVs, thereby presenting a significant challenge for clinical genetic counseling.
View Article and Find Full Text PDFCase Rep Ophthalmol Med
September 2025
Department of Ophthalmology and Visual Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
A 62-year-old female with retinitis pigmentosa presented for a low vision rehabilitation evaluation. An updated spectacle prescription, filters, and task lighting were beneficial, but the patient was left with outstanding needs. She noted that she had lost her independence and felt trapped within her own home with nobody around who could fully understand her situation.
View Article and Find Full Text PDFNat Commun
September 2025
Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, 90033, California, USA.
Introduction: Congenital Hypogonadotropic Hypogonadism (CHH) arises from defects in the synthesis, secretion, or action of gonadotropin-releasing hormone (GnRH), resulting in incomplete or absent pubertal development and various non-reproductive features. CHH is genetically heterogeneous, with over 50 genes implicated in its pathogenesis. This study aimed to elucidate the genetic variants of CHH in a cohort of patients from a single-center endocrinology unit.
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