A coefficient-free and continuous blood pressure estimation method based on the arterial lumen area model.

Oscillometry is the most popular technique for automatic blood pressure (BP) estimation. This method relies on recording the cuff deflation curve (CDC) from a high suprasystolic BP (SSBP) to a low subdiastolic BP (SDBP) and is very sensitive to noise caused by breathing, motion artifacts, muscle contraction and the environment. We developed a unified BP estimation method involving two integrated sub-procedures based on the arterial lumen area (ALA) model and applied it for continuous BP measurement. Our proposed method is coefficient free and continuous. No empirical coefficients are applied, and the CDC varies within a low-pressure range of 40-80 mm Hg, which can be sustainably imposed on our wrists. The first sub-procedure estimates the mean arterial pressure (MAP) and arterial compliance parameter b under a complete CDC period. In the second sub-procedure, the systolic BP (SBP) and diastolic BP (DBP) are estimated based on the dynamic-updated oscillometric waveform. We applied this method on 300 continuously oscillometric traces recorded from 20 male and female healthy subjects aged 20-60 years. The validated results were compared with those from a double stethoscope check. We observed mean absolute errors of 4.77 and 4.24 mm Hg in estimating the SBP and DBP, respectively.