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Generalized linear latent variable models (GLLVMs) offer a general framework for flexibly analyzing data involving multiple responses. When fitting such models, two of the major challenges are selecting the order, that is, the number of factors, and an appropriate structure for the loading matrix, typically a sparse structure. Motivated by the application of GLLVMs to study marine species assemblages in the Southern Ocean, we propose the Ordered Factor LASSO or OFAL penalty for order selection and achieving sparsity in GLLVMs. The OFAL penalty is the first penalty developed specifically for order selection in latent variable models, and achieves this by using a hierarchically structured group LASSO type penalty to shrink entire columns of the loading matrix to zero, while ensuring that non-zero loadings are concentrated on the lower-order factors. Simultaneously, individual element sparsity is achieved through the use of an adaptive LASSO. In conjunction with using an information criterion which promotes aggressive shrinkage, simulation shows that the OFAL penalty performs strongly compared with standard methods and penalties for order selection, achieving sparsity, and prediction in GLLVMs. Applying the OFAL penalty to the Southern Ocean marine species dataset suggests the available environmental predictors explain roughly half of the total covariation between species, thus leading to a smaller number of latent variables and increased sparsity in the loading matrix compared to a model without any covariates.
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http://dx.doi.org/10.1111/biom.12888 | DOI Listing |
JB JS Open Access
September 2025
Department of Orthopaedic Surgery, University of Miami Miller School of Medicine, Miami, Florida.
Background: Academic integrity is a cornerstone of scientific research. However, increasing competition may cause applicants seeking competitive positions to report their research contributions inaccurately. An orthopaedic research fellowship offers substantial value for medical students and recent medical graduates to strengthen their applications for a residency position.
View Article and Find Full Text PDFJ Pharm Policy Pract
September 2025
Division of Social and Administrative Pharmacy, Faculty of Pharmaceutical Sciences, Burapha University, Chonburi, Thailand.
Background: Although the 12-item Short Form Health Survey version 2 (SF-12v2) is suitable for measuring health status in the general Thai population, it has been evaluated using classical test theory. Rasch analysis, however, offers a psychometric testing method that converts ordinal scales to interval-level data without breaching parametric assumptions. Thus, this study aimed to assess the measurement properties of Thai SF-12v2 and SF-6D items derived from it among the general Thai population.
View Article and Find Full Text PDFFront Oncol
August 2025
Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany.
Purpose: Identifying radiomics features that help predict whether glioblastoma patients are prone to developing epilepsy may contribute to an improvement of preventive treatment and a better understanding of the underlying pathophysiology.
Materials And Methods: In this retrospective study, 3-T MRI data of 451 pretreatment glioblastoma patients (mean age: 61.2 ± 11.
J Pain Res
September 2025
Department of Anesthesiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, People's Republic of China.
Purpose: Postoperative hyperalgesia (POH) is a common clinical phenomenon that will increase the experience of patients' pain. Previous studies have confirmed that surgical site, opioid analgesics, gender, and age were risk factors of POH. Limited research has been investigated to prove the association between obstructive sleep apnea (OSA) and POH.
View Article and Find Full Text PDFAnal Chem
September 2025
National Key Laboratory of Laser Spatial Information, Harbin Institute of Technology, Harbin 150001, China.
In this paper, a single-quartz-enhanced photoacoustic-photothermal dual spectroscopy sensor based on a spherical acoustic resonator (SAR) is reported for the first time. The dual spectroscopy of quartz-enhanced photoacoustic spectroscopy (QEPAS) and quartz-enhanced photothermal spectroscopy (QEPTS), utilizing a single quartz tuning fork (QTF), eliminates the frequency mismatch issue that occurs when multiple QTFs are used. The dual spectroscopy model was constructed using the finite element method, which provides numerical simulation support for subsequent experiments.
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