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Article Abstract
GRAM domain proteins were reported as novel ER-PM tethers defining specific membrane contact sites (MCS) subdomains. GRAMD2a pre-marks the sites occupied by STIM1 at MCS and its ablation impairs STIM1 translocation, but not store-operated Ca entry. We discuss these apparently counterintuitive findings in the context of STIM/ORAI signaling at MCS.
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| http://dx.doi.org/10.1016/j.ceca.2018.04.002 | DOI Listing |
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