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Article Abstract
Antartin (), a new zizaane-type sesquiterpene, was isolated from sp. SCO736. The chemical structure of was assigned from the interpretation of 1D and 2D NMR in addition to mass spectrometric data. The relative stereochemistry of was determined by analysis of NOE data, while the absolute stereochemistry was decided based on a comparison of experimental and calculated electronic circular dichroism (ECD) spectra. Antartin () showed cytotoxicity against A549, H1299, and U87 cancer cell lines by causing cell cycle arrest at the G1 phase.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923417 | PMC |
| http://dx.doi.org/10.3390/md16040130 | DOI Listing |
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Department of Chemistry and Nano Science, Ewha Womans University, Seoul 03760, Korea.
Antartin (), a new zizaane-type sesquiterpene, was isolated from sp. SCO736. The chemical structure of was assigned from the interpretation of 1D and 2D NMR in addition to mass spectrometric data.
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