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http://dx.doi.org/10.1097/JCP.0000000000000884 | DOI Listing |
J Clin Psychopharmacol
June 2018
Centre of Evaluation and Information on Pharmacodependence-Addictovigilance of Paris (CEIP-A) Fernand Widal Hospital APHP Paris, France Centre of Evaluation and Information on Pharmacodependence-Addictovigilance of Paris (CEIP-A) Fernand Widal Hospital APHP Paris, France De
Eur J Neurosci
February 2005
Universités Bordeaux 1 & Victor Segalen Bordeaux 2, Laboratoire Physiologie et Physiopathologie de la Signalisation Cellulaire, UMR CNRS 5543, Equipe Neurobiologie Adaptative des Systèmes Moteurs, 33076 Bordeaux Cedex, France.
Isolated brainstem-spinal cord preparations were used to explore the coexistence of a direct and an indirect descending drive from the brainstem respiratory centre to cervical and thoracic respiratory motoneurons in the neonatal Sprague-Dawley rat. Polysynaptic spinal relay pathways from the respiratory centre were suppressed by selectively perfusing the cord with mephenesin (1 mM) or a solution enriched with Ca2+ and Mg2+. At birth, both direct and spinally relayed pathways are functional and contribute equally to the global descending respiratory drive.
View Article and Find Full Text PDFYakugaku Zasshi
March 1991
College of Pharmacy, Nihon University, Chiba-ken, Japan.
In reviewing recent progress concerning the motor system and drug action, the following subjects will be discussed on the basis of our data: 1) the mechanisms of action of mephenesin and baclofen, 2) baclofen and gamma-aminobutyric acid B (GABAB) receptor, 3) GABA-, benzodiazepine receptors, 4) control of spinal motor system by descending noradrenergic neuron, 5) pharmacology of the muscle spindle, and 6) pharmaco-metrics of centrally acting muscle relaxants.
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