Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Surface plasmon resonance is an optical technique that is utilized for detecting molecular interactions, such as interactions that occur between proteins or other classes of molecules. Binding of a mobile molecule (analyte) to a molecule immobilized on a thin metal film (ligand) changes the refractive index of the film. The angle of extinction of light that is completely reflected after polarized light impinges upon the film, is altered and monitored as a change in detector position for a dip in reflected intensity (the surface plasmon resonance phenomenon). Because the method strictly detects mass, there is no need to label the interacting components, thus eliminating possible changes of their molecular properties. In this chapter, we review essential SPR methodology and present applications to basic science and human disease.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/bs.apcsb.2017.07.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Gold nanoparticles-enhanced hollow fiber surface plasmon resonance sensor for highly sensitive detection of mercury(II) ions.
Analyst
September 2025
School of Information Science and Technology, Fudan University, 220 Handan Rd, Shanghai 200433, China.
Mercury(II) ions (Hg) are one of the most common and highly toxic heavy metal ions, which can contaminate the environment and damage the human health. Therefore, the precise detection of trace Hg concentration is particularly important. Herein, gold nanoparticles-enhanced silver-coated hollow fiber (HF) surface plasmon resonance (SPR) sensor was developed for the highly sensitive detection of Hg ions.
View Article and Find Full Text PDFAluminum surface lattice resonances for enhanced near-infrared performance in asymmetric environments.
Nanoscale
September 2025
Université Paris Cité, Laboratoire ITODYS, CNRS, F-75006 Paris, France.
Aluminum (Al) is a cost-effective alternative to noble metals for plasmonics, particularly in the ultraviolet (UV) and visible regions. However, in the near-infrared (NIR) region, its performance is hindered by interband transitions (IBTs) at around 825 nm, leading to increased optical losses and broad resonances. Surface lattice resonances (SLRs) offer a promising solution by enhancing the plasmonic quality factor (-factor) through coherent coupling of localized surface plasmon (LSP) modes with Rayleigh anomalies.
View Article and Find Full Text PDFSemiopen Ag@Au Plasmonic Nanotube Arrays Synergizing Molecular Confinement and Multimodal SERS for Lung Cancer Breath Diagnostics.
ACS Appl Mater Interfaces
September 2025
College of Engineering and Applied Sciences, Nanjing University, Nanjing 210093, P. R. China.
Exhaled breath analysis offers noninvasive, early lung cancer detection via volatile organic compound (VOC) biomarkers, surpassing blood-based methods. Surface-enhanced Raman spectroscopy (SERS) is ideal for this purpose, combining molecular fingerprint specificity with single-molecule sensitivity. However, conventional SERS substrates face a fundamental limitation: while porous materials such as metal-organic frameworks effectively adsorb VOCs through their subnanometer pores (0.
View Article and Find Full Text PDFMulti-omics and experimental validation reveal the mechanism of DanxiaTiaoban decoction in treating atherosclerosis.
Phytomedicine
August 2025
Cardiology Department, Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, China. Electronic address:
Background: Atherosclerosis (AS) is a leading risk factor for cardiovascular diseases globally, characterised by the accumulation of lipids and cholesterol in arterial walls, causing vascular narrowing and sclerosis along with chronic inflammation; this leads to increased risk of heart disease and stroke, significantly impacting patients' health. Danxia Tiaoban Decoction (DXTB), a traditional Chinese medicine (TCM) formula, has demonstrated positive clinical effects in treating AS; however, its mechanisms of action remain unclear.
Objective: To explore the potential mechanisms of action of DXTB in treating AS through multi-omics integration and experimental validation.
Glycoside hydrolase Ma3360 mediates immune evasion by Metarhizium anisopliae in insects.
Pestic Biochem Physiol
November 2025
National Key Laboratory of Green Pesticide, College of Plant Protection, South China Agricultural University, Guangzhou 510642, China. Electronic address:
Entomopathogenic fungi can precisely inhibit the cellular and humoral immune responses of host insects by secreting effector proteins, allowing them to overcome the innate immune barriers of their hosts. Nodule formation is an immune response primarily mediated by insect hemocytes, which can rapidly and efficiently capture invading pathogenic fungi in the hemocoel. However, the molecular mechanisms by which fungi inhibit insect nodule formation through the secretion of effector proteins remain unclear.
View Article and Find Full Text PDF