98%
921
2 minutes
20
Objective: To determine the predictive value of repeated abdominal ultrasonography in patients with multiple trauma and decreased level of consciousness (LOC).
Methods: This prospective cross-sectional study was conducted over a six-month period at Shahid Rajaee Trauma Hospital, Shiraz, Iran. We included hemodynamically stable blunt abdominal trauma patients with a decreased LOC (Glasgow Coma Scale ≤ 13) who were referred to the neurosurgery ICU ward. Included cases underwent 1 contrast-enhanced CT scan and two-time ultrasonographic study of the abdomen with an interval of 48 hours. The diagnostic accuracy of the ultrasonography was determined according to the CT-scan results.
Results: Overall 80 patients with mean age of 37.75 ± 18.67 years were included. There were 17 (21.3%) women and 63 (78.8%) men among the patients. Compared with the CT-Scan, the first ultrasonography showed a sensitivity of 60%, specificity of 80%, PPV of 16.60%, NPV of 96.80%, and a diagnostic accuracy of 70%. The same values for the second ultrasonographic study were 80%, 79%, 20%, 98%, and 79%, respectively. In 4 (5%) patients whose first ultrasonography and CT scan results were negative, the second ultrasonography was positive for injury.
Conclusion: In patients with blunt trauma to the abdomen, when the only indication of abdominal CT scan is a decreased LOC, two ultrasonographic studies can replace a CT imaging.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787360 | PMC |
http://dx.doi.org/10.29252/beat-060104 | DOI Listing |
Gastric Cancer
September 2025
Department for the Promotion of Medical Device Innovation, National Cancer Center Hospital East, Bunkyo City, Tokyo, Japan.
Background: Although many studies have developed logistic regression models for predicting complications using preoperative and intraoperative data, none have applied comprehensive perioperative information with machine learning (ML) to enable time-sequential predictions.
Methods: This study included patients undergoing gastric cancer surgery between 2013 and 2019 at two hospitals. Comprehensive perioperative data were collected.
Am J Respir Crit Care Med
September 2025
Aalborg University Hospital, Anaesthesia and Intensive Care, Aalborg, North Denmark Region, Denmark.
Rationale: In intensive care unit (ICU) patients lower oxygenation targets may impair long-term cognitive function, while higher targets may impair long-term pulmonary function.
Objectives: To assess the effects of a partial pressure of arterial oxygen (PaO) target of 60 vs 90 mmHg on one-year cognitive and pulmonary functions in ICU survivors of acute hypoxemic respiratory failure.
Methods: 3654 patients were randomized in the Handling Oxygenation Targets in the ICU and the Handling Oxygenation Targets in COVID-19 trials: 1916 (52.
Ann Am Thorac Soc
September 2025
University of California Los Angeles David Geffen School of Medicine, Medicine, Los Angeles, California, United States.
Rationale: Inflammation is central to chronic obstructive pulmonary disease (COPD) pathogenesis but incompletely represented in COPD prognostic models. Neutrophil to lymphocyte ratio (NLR) is a readily available inflammatory biomarker.
Objectives: To explore the associations of NLR with smoking status, clinical features of COPD, and future adverse outcomes.
PLoS One
September 2025
College of Intelligent Science and Control Engineering, Jinling Institute of Technology, Nanjing, China.
Traffic congestion frequently occurs in the drop-off zones of large integrated passenger hubs, posing significant challenges to the efficient utilization of lane space. This study develops a First-In-First-Out (FIFO) taxi drop-off decision-making model, incorporating both static and dynamic Logit frameworks grounded in panel data analysis. The model accounts for heterogeneity across vehicles, temporal variations, and spatial factors influencing drop-off decisions.
View Article and Find Full Text PDFAdv Ther
September 2025
Sanofi, Gentilly, France.
Introduction: No head-to-head studies comparing the efficacy of avalglucosidase alfa (AVA) with cipaglucosidase alfa + miglustat (Cipa+mig) have been conducted in patients with late-onset Pompe disease (LOPD). Two indirect treatment comparisons (ITCs) were conducted to estimate the effects of AVA versus Cipa+mig.
Methods: ITCs were conducted using simulated treatment comparisons (STCs), adjusting for differences in prognostic factors and treatment effect modifiers.