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Background: A significant surge in pertussis cases since early 2023 has raised serious public health concerns. To investigate the potential mechanisms contributing to this increased prevalence, we collected throat swab specimens from children exhibiting pertussis symptoms and conducted detailed molecular characterization.
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BackgroundGlaucoma is recognized as the second-leading cause of complete blindness in developed countries and a significant contributor to irreversible vision loss worldwide. Understanding the potential genetic links between neurodegenerative diseases, such as Parkinson's disease, and glaucoma is crucial for developing preventive strategies.MethodsThis study utilized data from Genome-Wide Association Studies databases, focusing on European populations without gender restrictions.
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Amyloid materials are formed from the aggregation of single proteins, yet contain polymorphisms where bulk properties are defined by a composition of multiple fibril types. Though desirable as a sustainable material, little is known about how various fibril types survive at high temperatures or in nonpolar solvents due to their highly similar molecular and nanoscale features. Here, we demonstrate that in situ two-dimensional infrared spectroscopy (2DIR), when paired with nanoscale microscopy, can determine the transition temperature of amyloid subpopulations without the use of labels.
View Article and Find Full Text PDFRelationship between biotransformation enzyme genes in polycyclic aromatic hydrocarbon metabolism, telomere length and missed abortion.
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View Article and Find Full Text PDFGenome-Wide Insights Into the Genes and Pathways Shaping Human Foveal Development: Redefining the Genetic Landscape of Foveal Hypoplasia.
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The University of Leicester Ulverscroft Eye Unit, School of Psychology and Vision Sciences, University of Leicester, Leicester, United Kingdom.
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