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http://dx.doi.org/10.1212/WNL.0000000000004213 | DOI Listing |
Neurology
August 2025
Stroke Center, Neurology Service, Department of Clinical Neurosciences, Lausanne University Hospital, Switzerland.
We describe an adult patient who developed widespread skin ulceration in the left trigeminal nerve distribution due to a Wallenberg syndrome from an acute ischemic stroke in the left lateral medulla. Trigeminal trophic syndrome is a rare consequence of a trigeminal nerve pathway injury characterized by the triad of persistent ulceration, anesthesia, and paresthesia of the same trigeminal dermatomes. It is an unusual complication of stroke that most likely developed in this patient from a combination of neurotrophic skin changes worsened by self-inflicted injury from scratching in a hypoesthetic region and by a psychiatric comorbidity.
View Article and Find Full Text PDFNeurology
August 2025
Neurology Department, Unidade Local de Saúde Gaia/Espinho, Porto, Portugal; and.
Autoimmune nodo-paranodopathy (AINP) associated with antibodies against pan-neurofascin (Ab-PanNF) is a rare subtype of autoimmune neuropathy. It can present as a severe, prolonged, and sometimes fatal disease. However, with appropriate treatment, it generally follows a monophasic course, and many patients achieve complete or near-complete recovery.
View Article and Find Full Text PDFNeurology
July 2025
Department of Neurology, Centro Hospitalar Universitário de Santo António, Porto, Portugal.
Cerebral amyloid angiopathy (CAA) is a common cause of lobar intracerebral hemorrhage (ICH) and cognitive impairment for which diagnostic criteria have been recently revised. A subset of CAA cases have superimposed inflammation in the form of CAA-related inflammation, which may result in a more severe clinical course. We present the case of a 61-year-old man who presented with subacute behavioral changes, motor aphasia, and right hemiparesis due to an ICH in the left superior frontal gyrus.
View Article and Find Full Text PDFNeurology
July 2025
Ear, Nose and Throat Department, Maastricht University Medical Centre, the Netherlands.
Transient neurologic symptoms are a commonly observed problem within neurology. It is less typical for these symptoms to be triggered by a certain movement. This case describes a 57-year-old man with a history of hypertension who presented for evaluation of posture-dependent left-sided weakness.
View Article and Find Full Text PDFNeurology
May 2025
Department of Clinical Neurosciences, University of Calgary, Alberta, Canada.
Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is an uncommon diagnosis in the differential for leptomeningeal enhancement. This case highlights the presentation, imaging features, and investigations important for diagnosis of GFAP astrocytopathy to ensure timely treatment of this corticosteroid-responsive disease. A 50-year-old man from Hong Kong presented with 10 days of progressive urinary retention, dysarthria, diplopia, and gait ataxia after a viral illness.
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