Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Purpose: Correlation of results of polymerase chain reaction for Mycobacterium tuberculosis (MTB PCR) with clinical features and treatment response in tubercular uveitis.
Methods: Retrospective case study.
Results: Among 56 patients, 31 (55.3%) had acute and 25 (44.6%) had chronic uveitis. Uveitis was unilateral in 40 (71.4%) and bilateral in the remaining 16 (28.6%). Anatomical subtypes of uveitis were: anterior in 10 (13.9%) eyes, intermediate in 9 (12.5%), posterior in 17 (23.6%), and pan uveitis in 36 (50%) eyes. MTB PCR was positive in 24 patients. There was an 80% correlation between clinical response to antitubercular therapy (ATT) and PCR results. Twenty-two patients with positive PCR had a good clinical response. The sensitivity and specificity was 73.3% and 92.3%, respectively.
Conclusions: The diagnosis of intraocular TB requires strong clinical suspicion with corroborative laboratory and radiological evidence. A positive PCR is reliable whereas negative results should be correlated with clinical features. An adequate response to ATT supports PCR results.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/09273948.2017.1287925 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Use of the i-PARIHS framework in nutrition and dietetics research and practice: A citation analysis of the literature and case studies.
Nutr Clin Pract
September 2025
Centre for Health Services Research, University of Queensland, Brisbane, Queensland, Australia.
Theoretical approaches can help to plan, guide, and evaluate implementation projects that target real-world practice problems. This paper provides an overview of the integrated Promoting Action on Research Implementation in Health Services (i-PARIHS) framework and summarizes its use in nutrition and dietetics research and practice. A narrative summary of its use was compiled from the published literature based on citations from two key reference sources of the i-PARIHS framework.
View Article and Find Full Text PDFPsychological and neurophysiological measures of emotion dysregulation in borderline personality disorder and posttraumatic stress disorder.
Borderline Personal Disord Emot Dysregul
September 2025
German Center for Mental Health (DZPG), partner site Munich, Munich, Germany.
Background: Emotion dysregulation is a central feature in trauma-associated disorders such as posttraumatic stress disorder (PTSD) and borderline personality disorder (BPD). However, it remains unclear whether emotion dysregulation is a transdiagnostic phenomenon closely linked to childhood trauma, or if disorder-specific alterations in emotion processing exist. Following a multimethodological approach, we aimed to assess and compare the reactivity to and regulation of emotions between patients with BPD and PTSD, as well as healthy controls, and identify associations with childhood trauma.
View Article and Find Full Text PDFMonitoring Gait Recovery After Total Knee Arthroplasty Using Wearable Sensors: Responsiveness of Gait Accelerations.
J Orthop Res
September 2025
Interdisciplinary Orthopedics, Department of Orthopedics Surgery, Aalborg University Hospital, Aalborg, Denmark.
Functional recovery after total knee arthroplasty (TKA) varies widely among individuals, and traditional assessments often fail to detect subtle changes in real-world walking ability. Wearable sensors offer continuous and objective tracking of gait outside of clinical settings. In this prospective, longitudinal study, thirty-one patients undergoing unilateral TKA wore thigh-mounted accelerometers continuously from 2 weeks before surgery through 90 days postoperatively.
View Article and Find Full Text PDFLONP1 Variants Are Associated With Clinically Diverse Phenotypes.
Clin Genet
September 2025
Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
LONP1 encodes a mitochondrial protease essential for protein quality control and metabolism. Variants in LONP1 are associated with a diverse and expanding spectrum of disorders, including Cerebral, Ocular, Dental, Auricular, and Skeletal anomalies syndrome (CODAS), congenital diaphragmatic hernia (CDH), and neurodevelopmental disorders (NDD), with some individuals exhibiting features of mitochondrial encephalopathy. We report 16 novel LONP1 variants identified in 16 individuals (11 with NDD, 5 with CDH), further expanding the clinical spectrum.
View Article and Find Full Text PDFPhenotypic age acceleration as a novel predictor of benign prostatic hyperplasia: a prospective cohort study.
Geroscience
September 2025
Department of Urology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
This study aims to investigate the predictive value of combined phenotypic age and phenotypic age acceleration (PhenoAgeAccel) for benign prostatic hyperplasia (BPH) and develop a machine learning-based risk prediction model to inform precision prevention and clinical management strategies. The study analyzed data from 784 male participants in the US National Health and Nutrition Examination Survey (NHANES, 2001-2008). Phenotypic age was derived from chronological age and nine serum biomarkers.
View Article and Find Full Text PDF