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This study aimed to assess the role of pre-designed route on computer tomography urography (CTU) in the ultrasound-guided percutaneous nephrolithotomy (PCNL) for renal calculus.From August 2013 to May 2016, a total of 100 patients diagnosed with complex renal calculus in our hospital were randomly divided into CTU group and control group (without CTU assistance). CTU was used to design a rational route for puncturing in CTU group. Ultrasound was used in both groups to establish a working trace in the operation areas. Patients' perioperative parameters and postoperative complications were recorded.All operations were successfully performed, without transferring to open surgery. Time of channel establishment in CTU group (6.5 ± 4.3 minutes) was shorter than the control group (10.0 ± 6.7 minutes) (P = .002). In addition, there was shorter operation time, lower rates of blood transfusion, secondary operation, and less establishing channels. The incidence of postoperative complications including residual stones, sepsis, severe hemorrhage, and perirenal hematoma was lower in CTU group than in control group.Pre-designing puncture route on CTU images would improve the puncturing accuracy, lessen establishing channels as well as improve the security in the ultrasound-guided PCNL for complex renal calculus, but at the cost of increased radiation exposure.
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http://dx.doi.org/10.1097/MD.0000000000007215 | DOI Listing |
BMJ Open
September 2025
Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Background: The evidence for the optimal duration of psychotherapy for borderline personality disorder (BPD) is scarce. Two previous trials have compared different durations of psychotherapy. The first compared 6 months versus 12 months of dialectical behaviour therapy for BPD (the FASTER trial).
View Article and Find Full Text PDFJ Am Coll Cardiol
August 2025
Department of Advanced Biomedical Sciences, University of Naples "Federico II", Italy; "Federico II" University Hospital, Naples, Italy. Electronic address:
Background: Dual antiplatelet therapy (DAPT) is recommended for patients undergoing percutaneous coronary intervention (PCI), although its optimal duration remains uncertain.
Objectives: We performed a randomized trial comparing a personalized duration of DAPT, based on a risk score, for 3-, 6-, or 24-months with a standard duration of DAPT for 12 months after PCI.
Methods: We randomly assigned 2,107 patients undergoing PCI to receive either a personalized or a standard DAPT.
Int J Cardiovasc Imaging
September 2025
Department of Cardiology, Bern University Hospital, Inselspital, University of Bern, Bern, Switzerland.
Higher on-treatment levels of low-density lipoprotein cholesterol in statin-treated patients were reportedly associated with the occurrence of neoatherosclerosis after drug-eluting stent (DES) implantation. We aimed to investigate the impact of alirocumab added to high-intensity statin therapy on neoatherosclerosis formation among patients with acute myocardial infarction (AMI) treated with DES. This was a pre-specified substudy of the PACMAN-AMI trial, a randomized, double-blind trial comparing alirocumab versus placebo added to high-intensity statin therapy in AMI patients.
View Article and Find Full Text PDFJ Pediatr Urol
July 2025
Department of Pediatric Surgery, First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, China. Electronic address:
Objective: To compare the efficacy of laparoscopic proximal versus distal ureteroureterostomy in the treatment of complete renal-ureteral duplication malformation in children.
Method: This retrospective study included 72 pediatric patients diagnosed with complete renal-ureteral duplication malformation at the First Affiliated Hospital of Zhengzhou University between January 2014 and December 2021. Diagnosis was confirmed through various imaging studies, including ultrasound, diuretic renography, CT urography (CTU), magnetic resonance urography (MRU), and voiding cystourethrography (VCUG).
Support Care Cancer
August 2025
Macquarie University Clinical Trials Unit (CTU), Faculty of Medicine and Health Sciences, Macquarie University & Macquarie University Hospital, New South Wales, Macquarie, 2109, Australia.
Purpose: As more individuals survive prostate cancer, addressing survivorship concerns like cancer-related cognitive impairment (CRCI) becomes increasingly important. Identifying modifiable psychosocial factors related to CRCI is critical in devising targeted non-pharmacological interventions. We aimed to investigate the psychosocial factors associated with perceived cognitive functioning in prostate cancer survivors (PCS).
View Article and Find Full Text PDF