Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
San Leng powder extract has been used as medicinal compound for the prevention and treatment of cancers. The antitumor activity of SLPE was determined by treating BALB/C mice harboring a human gastric cancer xenograft with SPLE for 17 days. Mice were also treated with fluorouracil (5-Fu, 25 mg/kg) or a combination of SLPE and 5-Fu. Our results indicate that the inhibition of tumor growth by SLPE might be due to a block in the cell cycle and the induction of apoptosis. These results suggest that SLPE might be useful in the treatment of gastric cancer.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439070 | PMC |
| http://dx.doi.org/10.1155/2017/1052125 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Sleep chart of biological aging clocks across organs and omics.
medRxiv
August 2025
Laboratory of AI and Biomedical Science (LABS), Columbia University, New York, NY, USA.
Optimal sleep plays a vital role in promoting healthy aging and enhancing longevity. This study proposes a Sleep Chart to assess the relationship between sleep duration and 23 biological aging clocks across 17 organ systems or tissues and 3 omics data types (imaging, proteomics, and metabolomics). First, a systemic, U-shaped pattern shows that both short (<6 hours) and long (>8 hours) sleep duration are linked to elevated biological age gaps (BAGs) across 9 brain and body systems and 3 omics types, with optimal sleep time varying by organ and sex ([6.
View Article and Find Full Text PDFClinical Parameters Associated With Intracranial Progression Burden Following an Initial Stereotactic Radiosurgery Course in a Multi-institutional Brain Metastases Cohort.
Adv Radiat Oncol
September 2025
Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina.
Purpose: Following initial stereotactic radiosurgery (SRS), risk factors for high-burden intracranial progression (ICP) necessitating whole brain radiation remain poorly characterized. We hypothesize that specific clinical parameters at initial SRS are associated with high-burden ICP-defined as either ≥5 brain metastases (BMs) (ICP5) or ≥11 BMs (ICP11).
Materials And Methods: Across 2 institutions, we retrospectively identified all patients completing an initial SRS course from January 2015 to December 2020.
Activation of IL-17+ ILC subsets in IL-18R-deficient mice during fungal allergen exposure.
bioRxiv
July 2025
Divison of Allergy and Immunology, Department of Medicine, University of California San Diego, La Jolla, CA.
Group 2 innate lymphoid cells (ILC2s) are critical players during type 2 inflammation present in most forms of asthma. ILC2s are tissue-resident cells that produce cytokines IL-5 and IL-13 critical to eosinophilic airway inflammation, mucus production, remodeling, and hyperresponsiveness. Though each ILC subset (ILC1s, ILC2s, ILC3s) is identified by specific transcription factors, cell surface receptors and cytokine profiles, functional plasticity between ILC subtypes occurs in various contexts.
View Article and Find Full Text PDFReply to Fan : Assessment of the Neuroprotective Effect of CPAP in OSA: Can Static Metrics Map Dynamic Pathology?
Am J Respir Crit Care Med
July 2025
Otolaryngology Institute, Shanghai Jiao Tong University, Department of Otolaryngology, Affiliated Sixth People's Hospital, Shanghai, China;
Rest-activity rhythms are stronger in Mexican American compared to Non-Hispanic White and Black participants: a cross-sectional study.
Sleep
July 2025
Department of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, CA, United States.
Study Objectives: This study aimed to investigate differences in rest-activity rhythms (RAR), key circadian rhythm markers, across race/ethnicity and sex in a diverse community-based cohort of older adults.
Methods: We examined RAR (amplitude [strength of activity], mesor [level of activity], acrophase [time of peak activity], and pseudo-F [robustness of activity]) derived from the extended cosinor model based on ≥4 24-hour periods of wrist actigraphy among 856 participants (≥50 years) in the Dormir Study. We conducted linear and multinomial logistic regression models adjusted for socioeconomic status, health conditions, and sleep-related factors.