Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Stroke is the second leading cause of death worldwide, with 10% of neurologic events occurring in adults aged 18-49 years. The incidence in this age group has risen over the last 2 decades (while falling in the aged), despite improved diagnostic capacity and greater ability to treat it medically and surgically. We are unaware of any modern data regarding the risk factors and outcomes after carotid artery surgery in this demographic. We sought to evaluate the contemporary characteristics and outcomes of young adults undergoing carotid surgery.
Methods: Retrospective analysis of patients aged 18-49 years who underwent carotid surgery from 2005 to 2015. We collected demographics, indications, and outcomes, comparing them to previously published series.
Results: Sixteen patients were with the mean age of 46 (41-49) years, and 44% were male. Most were Caucasian (88%) and smokers (94%), consuming 1.3 packs/day with a mean pack-year history of 32 years (10-100). Average body mass index was 29. The majority (81%) were symptomatic prior to surgery (69% of these were strokes). Complications after surgery were hyperperfusion (1) and one deep vein thrombosis. Compared to young patients treated from 1973 to 1990s, we found significantly more female patients (P < 0.001) and more strokes (P < 0.04) leading to the procedure, while smoking remained the most prevalent risk factor.
Conclusions: Carotid artery surgery in young patients continues to be associated with symptomatic stenosis and smoking; however, compared to 2-4 decades ago it may be more common in young females, and following a stroke. This may be from an increased prevalence of female smoking and improved neuroimaging.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.avsg.2017.01.017 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clay-based hemostatic agents: Fabrication, mechanisms, and evidence.
Biomater Adv
August 2025
School of Mechanical Engineering and Mechanics, Xiangtan University, Xiangtan 411105, China. Electronic address:
Hemorrhagic control remains a serious concern in emergency medicine and combat trauma management, where achieving rapid hemostasis significantly impacts patient survival outcomes. While conventional interventions including direct manual compression and tourniquet application demonstrate clinical efficacy in routine scenarios, their limitations become apparent when managing catastrophic hemorrhage or anatomically complex injuries. Mineral-based hemostatic agents, particularly clay-derived rapid hemostats, have emerged as a promising therapeutic modality that synergizes ancestral wound management practices with contemporary material engineering.
View Article and Find Full Text PDFThe contemporary use of emergency pericardiocentesis in trauma: A nationwide trend analysis.
Am J Emerg Med
August 2025
Department of Surgery, University of Southern California, Los Angeles, CA, USA; Division of Acute Care Surgery, Los Angeles General Medical Center, CA, USA. Electronic address:
Background: Pericardiocentesis is a critical skill taught by the Advanced Trauma Life Support (ATLS®) course, yet substantial knowledge gaps exist regarding recent practice changes and indications for pericardiocentesis. This study aims to characterize contemporary practice patterns and nationwide trends in the use of emergency pericardiocentesis in trauma.
Methods: A retrospective study of the National Trauma Data Bank (2011-2022) identified patients undergoing pericardiocentesis within 48 h of arrival prior to any cardiac repair surgery.
Background: Most previous mortality research in eating disorders involves individuals attending specialist treatment services. Data linkage across jurisdictional health databases at a population level improves the generalisability of findings.
Aims: To investigate mortality risk and causes of death for people with an eating disorder across a large geographic region using administrative health datasets.
Predicting massive blood transfusions in liver transplantation: the McCluskey Risk Index revised 20 years later.
Blood Transfus
July 2025
Transplant Anesthesia and Critical Care, Azienda Ospedaliera Universitaria Pisana, University School of Medicine, Pisa, Italy.
Background: Liver transplantation (LT) is a life-saving procedure for end-stage liver disease (ESLD), yet massive perioperative transfusions (MT) remain a significant concern. The McCluskey Risk Index (McRI), a widely used tool for predicting MT, was developed nearly two decades ago and does not fully account for recent advancements in LT practices and patient demographics. This study aims to evaluate the validity of the McRI in a contemporary LT cohort and propose a revised McRI (revMcRI) incorporating additional predictors.
View Article and Find Full Text PDFComparison of the efficacy of mFOLFOX-6 and mDCF regimens in the treatment of metastatic gastric cancer: a multicenter retrospective study.
Ther Adv Med Oncol
August 2025
Department of Medical Oncology, Mehmet Akif İnan Research and Training Hospital, Şanlıurfa, Turkey.
Background: Metastatic gastric cancer (GC) and gastroesophageal junction (GEJ) cancer are associated with a poor prognosis. Recent advancements in treatment have incorporated trastuzumab, anti-PD-1 agents, and anti-claudin therapies alongside chemotherapy (ChT), significantly improving outcomes. Contemporary studies predominantly employ doublet ChT as the backbone for these regimens, although historically triplet ChT regimens have been favored, particularly in younger patients requiring rapid tumor shrinkage.
View Article and Find Full Text PDF