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Shipping noise and wind are the dominant sources of ocean noise in the frequency band between 20 and 500 Hz. This paper analyzes noise in that band using data from the SPICEX experiment, which took place in the North Pacific in 2004-2005, and compares the results with other North Pacific experiments. SPICEX included vertical arrays with sensors above and below the surface conjugate depth, facilitating an analysis of the depth dependence of ambient noise. The paper includes several key results. First, the 2004-05 noise levels at 50 Hz measured in SPICEX had not increased relative to levels measured by Morris [(1978). J. Acoust. Soc. Am. 64, 581-590] at a nearby North Pacific site three decades earlier, but rather were comparable to those levels. Second, at 50 Hz the noise below the conjugate depth decreases at a rate of -9.9 dB/km, which is similar to the rate measured by Morris and much less than the rate measured by Gaul, Knobles, Shooter, and Wittenborn [(2007). IEEE J. Ocean. Eng. 32, 497-512] for the CHURCH OPAL experiment. Finally, the paper describes the seasonal trends in noise over the year-long time series of the measurements.
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http://dx.doi.org/10.1121/1.4976706 | DOI Listing |
Adv Ther
September 2025
Bristol Myers Squibb, Princeton, NJ, 08540, USA.
Background And Objectives: Deucravacitinib, a first-in-class, oral, selective, allosteric tyrosine kinase 2 inhibitor, demonstrated efficacy across the primary endpoint and all key secondary endpoints in the phase 2 PAISLEY SLE trial in patients with active systemic lupus erythematosus (SLE). Here, we describe 2 phase 3 trials [POETYK SLE-1 (NCT05617677), POETYK SLE-2 (NCT05620407)] which will assess the efficacy and safety of deucravacitinib in patients with active SLE. These phase 3 trials have been designed to replicate the successful elements of the phase 2 trial, including its glucocorticoid-tapering strategy and disease activity adjudication.
View Article and Find Full Text PDFEvol Appl
September 2025
National Oceanographic and Atmospheric Administration, National Marine Fisheries Service Southwest Fisheries Science Center La Jolla California USA.
The spatial structure and dynamics of populations are important considerations when defining management units in organisms that are harvested as natural resources. In the Eastern Pacific, Pacific Sardine range from Chile to Alaska, the northernmost state of the United States (U.S.
View Article and Find Full Text PDFAsia Pac J Ophthalmol (Phila)
September 2025
Department of ophthalmology, Sarawak General Hospital, Kuching, Malaysia.
Purpose: To determine Asia Pacific cataract surgeons' attitudes toward surgical waste and toward reusing supplies and pharmaceuticals.
Design: Multinational survey of APAO members METHODS: An online survey link was distributed to APAO members through their national ophthalmology societies. Responses were deidentified and compared with those from identical survey questionnaires previously distributed to North American and European cataract surgeons.
Prev Med
September 2025
Department of Pharmacy, Taoyuan General Hospital, Ministry of Health and Welfare, No. 1492, Zhongshan Rd., Taoyuan 33004, Taiwan. Electronic address:
Objective: Middle-aged and older adults living with HIV in the Western Pacific Region (WPR) are experiencing accelerated aging and a rising burden of non-communicable disease (NCD)-related comorbidities. This systematic review and meta-analysis aimed to assess the burden of major NCDs-measured by prevalence, incidence, and mortality-among people living with HIV(PLWH) aged 40 years and older, in comparison to their HIV-negative counterparts.
Methods: A comprehensive literature search was conducted across Medline (1966-), Embase (1974-), Cochrane Library (1996-), Epistemonikos (established in 2012, with retrospective coverage), and Web of Science (1900-) to identify relevant studies published up to May 9, 2025.
Sports Med
September 2025
Harvard Medical School, Boston, USA.
Background: Physical training influences competitive marathon performance, including training volume and training frequency changes (TFCs) pre-race. Training intensity distribution (i.e.
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