Bioactive constituents from transformed root cultures of Nepeta teydea.

Phytochemistry

Instituto de Productos Naturales y Agrobiología, CSIC, Avda. Astrofísico F. Sánchez 3, 38206, La Laguna, Tenerife, Canary Islands, Spain.

Published: January 2017


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Article Abstract

A phytochemical study of an extract from transformed root cultures of Nepeta teydea, induced by Agrobacterium rhizogenes, led to the isolation of the following new compounds: the sesquiterpene (-)-cinalbicol, the diterpene teydeadione (6,11,14-trihydroxy-12-methoxy-abieta-5,8,11,13,15-penten-7-one), a degraded C23-triterpene (teydealdehyde) and three fatty acid esters of lanosta-7,24-dien-3β-ol. The propyl ester of rosmarinic acid was also isolated for the first time from a natural source. In addition, two dehydroabietane diterpenes, eight triterpenes and eighteen known phenolic compounds were obtained. The antifeedant, cytotoxic and phytotoxic activities of the isolated compounds have also been investigated.

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http://dx.doi.org/10.1016/j.phytochem.2016.10.008DOI Listing

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