A Review on the Sex Differences in Organ and System Pathology with Alcohol Drinking.

Curr Drug Abuse Rev

Department of Medicine, Pharmacology and Toxicology, University of Louisville School of Medicine, 505 S. Hancock St. CTR Room 503, Louisville KY 40202. United States.

Published: May 2018


Article Synopsis

  • Alcohol consumption has harmful effects on both physical and mental health, with notable differences between males and females.
  • Research indicates that the severity of these consequences can vary by sex, impacting mental health and organ systems differently for each gender.
  • Increased awareness and studies focusing on females have led to a better understanding of the dynamics of drinking and its hazardous effects, highlighting the importance of considering sex in alcohol-related research.

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Article Abstract

Hazardous consequences of alcohol consumption adversely influence overall health, specifically physical and mental health. Differences in alcohol consumption and manifestations in pathology have been observed between males and females, however research on understanding these differences is limited. Negative consequences of alcohol consumption have now been studied including sex as a significant factor. Some studies have shown differences in the severity of consequences of alcohol consumption between the sexes, both in the mental consequences and changes/ injury in various organ systems. Over time, reports in females on both the dynamics of drinking and on the hazardous consequences of alcohol consumption have grown, primarily because of more awareness, better observation, and the inclusion of sex as a factor in scientific investigations. This paper reviews role of sex differences in pathophysiological and behavioral consequences of alcohol drinking.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894513PMC
http://dx.doi.org/10.2174/1874473710666170125151410DOI Listing

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