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Article Abstract
A 52-yr-old female Nile hippopotamus ( Hippopotamus amphibious ) was presented for acute onset anorexia, depression, lethargy, instability, and weakness in the pelvic limbs. Clinical signs were rapidly progressive, despite empiric therapy with anti-inflammatory medications, resulting in the death of the animal. Gross necropsy evaluation revealed two tan, firm masses in the cerebellum and mesencephalon and a single mass in the right cranial adrenal gland. All three masses had a similar histologic morphology, and immunohistochemical investigation confirmed the general diagnosis of an adenocarcinoma, but the exact cell of origin remains unclear. In addition, there was evidence of neuroendocrine differentiation in the adrenal gland and not in the brain. These findings suggest either two distinct neoplastic populations or a metastasizing adenocarcinoma with focal endocrine differentiation. In dogs, anal sac and clitoral adenocarcinomas have been reported to undergo focal endocrine differentiation, and both can cause widespread metastasis while the primary lesion can be small. A small neoplasm of these glands may have been missed on gross examination.
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| http://dx.doi.org/10.1638/2015-0256.1 | DOI Listing |
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Article Synopsis
- * A study conducted in the Dhidhessa Wildlife Sanctuary between 2021 and 2022 estimated the hippo population and analyzed habitat suitability, finding 231 hippos during the dry season and 133 during the wet season, with most observed in savanna grasslands and riverine forests.
- * The research concluded that a large portion of the habitat in the sanctuary is unsuitable for hippos due to human interference, emphasizing the need for creating a buffer zone to protect their living environment.