Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Metasurfaces with tunable spatial phase functions could benefit numerous applications. Currently, most approaches to tuning rely on mechanical stretching which cannot control phase locally, or by modulating the refractive index to exploit rapid phase changes with the drawback of also modulating amplitude. Here, we propose a method to realize phase modulation at subwavelength length scales while maintaining unity amplitude. Our device is inspired by an asymmetric Fabry-Perot resonator, with pixels comprising a scattering nanopost on top of a distributed Bragg reflector, capable of providing a nearly 2π nonlinear phase shift with less than 2% refractive index modulation. Using the designed pixels, we simulate a tunable metasurface composed of an array of moderately coupled nanopost resonators, realizing axicons, vortex beam generators, and aspherical lenses with both variable focal length and in-plane scanning capability, achieving nearly diffraction-limited performance. The experimental feasibility of the proposed method is also discussed.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215393PMC
http://dx.doi.org/10.1038/srep40174DOI Listing

Publication Analysis

Top Keywords

phase
6
tunable metasurfaces
4
metasurfaces subwavelength
4
subwavelength phase
4
phase shifters
4
shifters uniform
4
uniform amplitude
4
amplitude metasurfaces
4
metasurfaces tunable
4
tunable spatial
4

Similar Publications

Refractory cytomegalovirus (CMV) infection is a severe complication following umbilical cord blood transplantation (UCBT). Antiviral agents, the standard first-line therapy, are limited by toxicity and resistance without robust T-cell immunity. We evaluated third-party donor (TPD)-derived CMV-specific T cells (CMVSTs) as a treatment option.

View Article and Find Full Text PDF

Spirulina is considered a superfood due to its chlorophylls. Two new methods for the determination of chlorophylls and β-carotene were developed here, one based on in-tube solid-phase microextraction (IT-SPME) coupled online to nanoliquid chromatography (nanoLC) with diode array detection (DAD), and the other on ultraviolet-visible diffuse reflectance spectroscopy (UV-vis DRS). A protocol to extract the pigments from spirulina was proposed using ethanol (1.

View Article and Find Full Text PDF

A rapid and specific liquid chromatography-tandem mass spectrometry method with a wide linear range was developed and validated for the simultaneous quantification of Vitamin K1 (VK1) trans- and cis- isomers in human plasma. Bovine serum albumin solution (15%) served as a surrogate matrix for preparing the calibrators to establish the quantitative curves. After liquid-liquid extraction, VK1 trans- and cis- isomers in plasma samples were separated on a ChromCore C30 column (15 cm × 4.

View Article and Find Full Text PDF

Phase I dose escalation trials in oncology generally aim to find the maximum tolerated dose. However, with the advent of molecular-targeted therapies and antibody drug conjugates, dose-limiting toxicities are less frequently observed, giving rise to the concept of optimal biological dose (OBD), which considers both efficacy and toxicity. The estimand framework presented in the addendum of the ICH E9(R1) guidelines strengthens the dialogue between different stakeholders by bringing in greater clarity in the clinical trial objectives and by providing alignment between the targeted estimand under consideration and the statistical analysis methods.

View Article and Find Full Text PDF

Chrysotobibenzyl, a bioactive ingredient from Dendrobium chrysotoxum, exhibits potent anti-tumor activity. However, its metabolic profiles remain unelucidated. This study aimed to disclose the metabolic fates of chrysotobibenzyl using human liver fractions.

View Article and Find Full Text PDF