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Simple motor tics are sudden, nonrhythmic jerk like movements that are often preceded by premonitory urge and can be voluntarily suppressed. Some clinical characteristic of tics such as variability of movement, distractibility and fluctuating course can mimic functional movement disorders. Here we report a case of motor tics where the physiological approach in addition to careful clinical assessments is helpful to support the diagnosis of tic.
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http://dx.doi.org/10.1016/j.cnp.2016.04.001 | DOI Listing |
BMJ Open
September 2025
NIHR MindTech Medtech Co-operative, Institute of Mental Health, University of Nottingham, Nottingham, UK.
Objectives: Chronic tic disorders (CTDs)-such as Tourette Syndrome (TS)-are neurodevelopmental disorders affecting at least 1% of the population, causing repetitive involuntary movements and vocalisations known as tics. This study aimed to explore the lived experiences of accessing healthcare for people with CTD or TS and their families in the United Kingdom (UK), as part of a larger programme of work to inform change to healthcare services for this population.
Design: Informed and designed with extensive patient and public involvement, the design utilised qualitative research using focus groups.
Front Psychiatry
August 2025
Clinic of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.
Background: Tourette Syndrome (TS) is a childhood onset chronic disorder in which motor and vocal tics co-occur. Cannabinoids are a potential therapeutic option for otherwise treatment resistant patients. However, there is an ongoing debate regarding potential side effects.
View Article and Find Full Text PDFResuscitation
August 2025
Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, England.
Aim: To systematically review and appraise the measurement properties, interpretability, and feasibility of outcome measurement instruments (OMIs) for screening neurocognitive function among adult survivors of out-of hospital cardiac arrest (OHCA).
Methods: Online databases were searched (MEDLINE, EMBASE, CENTRAL, CINAHL, PsychINFO) from inception - August 23, 2024. Included articles evaluated measurement properties, interpretability (assigning meaning to scores), and/or feasibility (ease of application) of multidomain instruments for screening neurocognitive function among OHCA survivors.
Front Immunol
August 2025
Wenzhou Medical University, Wenzhou, Zhejiang, China.
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy characterized by poor prognosis, strong resistance to therapy, and a dense immunosuppressive tumor microenvironment (TME). A small subset of cells known as cancer stem cells (CSCs), or tumor-initiating cells (TICs), are increasingly recognized as key contributors to tumor initiation, metastasis, immune evasion, and treatment failure. These cells are defined by their self-renewal capacity, plasticity, and resistance to chemotherapeutic and targeted therapies.
View Article and Find Full Text PDFJ Evid Based Soc Work (2019)
August 2025
Center for Student Beloning, American University, Washington, DC, USA.
Background: Trauma-Informed Care (TIC) is frequently conceptualized as a clinical intervention targeting individual psychological harm. While valuable in clinical contexts, this framing restricts TIC's broader capacity for systemic and structural transformation.
Objective: This article reframes TIC as a structural disruption strategy-an equity-driven, systems-level intervention that redefines how health is understood, delivered, and governed.