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A number of atypical antipsychotics have been associated with peripheral edema. The exact cause is not known. We report two cases of olanzapine-induced edema and a brief review of atypical antipsychotic-induced edema, possible risk factors, etiology, and clinical features. The recommendation is given on different methods of managing this side effect.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904752 | PMC |
http://dx.doi.org/10.4103/0253-7176.183089 | DOI Listing |
Am J Case Rep
August 2025
Department of Hepatobiliary Surgery, Hospital Nossa Senhora das Graças, Curitiba, PR, Brazil.
BACKGROUND Immunotherapy has seen an exponential increase recently, as has the study of its associated adverse effects. Although a wide range of reactions to immunotherapy has been described, reports of immune-mediated focal pancreatitis remain rare. Autoimmune pancreatitis related to immune checkpoint inhibitors occurs because of the hyperactivation of T lymphocytes, which act against pancreatic cells, causing inflammation.
View Article and Find Full Text PDFJ Clin Immunol
August 2025
Department of Allergy & Immunology, Department of Dermatology, Huashan Hospital, Fudan University, 12 Middle Urumqi Road, Shanghai, 200040, P.R. China.
Hereditary angioedema with normal C1 inhibitor (HAE-nC1-INH) is a rare and genetically heterogeneous disorder with an incomplete molecular understanding. This study aimed to identify novel genetic variants associated with HAE-nC1-INH, characterize their clinical manifestations, and evaluate real-world treatment responses. Whole-exome sequencing of 27 HAE patients, including eight with HAE-nC1-INH, identified four previously unreported MYOF variants and additional pathogenic variants in KNG1 and HS3ST6, expanding the genetic spectrum of the disease.
View Article and Find Full Text PDFCureus
July 2025
Department of General Internal Medicine, Kobe City Medical Center General Hospital, Kobe, JPN.
Infectious mononucleosis, caused by Epstein-Barr virus (EBV), is a common infection in young adults. It typically presents with a self-limiting course characterized by fevers, pharyngitis, and lymphadenopathy. While mildly elevated liver enzymes are a common complication, cholestatic hepatitis and clinical jaundice are rare in EBV infection.
View Article and Find Full Text PDFJ Assoc Physicians India
July 2025
Additional Professor, Department of Pathology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Over the past few years, there has been a significant rise in the prevalence of human fungal infections worldwide, largely due to factors such as the acquired immunodeficiency syndrome (AIDS) pandemic, widespread use of antibacterial agents, and the utilization of chemotherapeutic agents for treating neoplastic diseases. Histoplasmosis, attributed to the dimorphic fungus , is one such opportunistic fungal infection. It is endemic to regions along the "Ohio" and "Mississippi" river valleys and is frequently located in soil tainted by bat or bird feces.
View Article and Find Full Text PDFAnn Afr Med
August 2025
Department of General Medicine, Dr. D.Y. Patil Vidyapeeth, Pune, Maharashtra, India.
Kikuchi-Fujimoto disease (KFD), or histiocytic necrotizing lymphadenitis, is a rare, benign, and self-limiting condition that typically affects young women and is uncommon in children or males. We report the case of a 15-year-old boy who presented with generalized lymphadenopathy involving cervical, axillary, submandibular, and inguinal nodes, along with mild fever and pain. A series of fine-needle aspiration cytology and lymph node biopsies over 3 years initially showed reactive and acute lymphadenitis.
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