Generalized Lymphadenopathy in a Young Boy: A Rare Presentation of Kikuchi-Fujimoto Disease.

Kikuchi-Fujimoto disease (KFD), or histiocytic necrotizing lymphadenitis, is a rare, benign, and self-limiting condition that typically affects young women and is uncommon in children or males. We report the case of a 15-year-old boy who presented with generalized lymphadenopathy involving cervical, axillary, submandibular, and inguinal nodes, along with mild fever and pain. A series of fine-needle aspiration cytology and lymph node biopsies over 3 years initially showed reactive and acute lymphadenitis.