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Dashboards are commonly used in healthcare to monitor and respond to safety and quality data, but few data describe how to best implement dashboards in home infusion therapy. We developed a dashboard for a collaborative of home infusion agencies to monitor an important safety outcome, central line-associated bloodstream infections (CLABSI). We used the Technology Acceptance Model (TAM) to understand key components of implementing a CLABSI surveillance dashboard in a home infusion therapy environment.
View Article and Find Full Text PDFRole of EDTA lock solution in preventing catheter-related bloodstream infections or central line-associated bloodstream infections: a systematic review and meta-analysis.
Infect Control Hosp Epidemiol
September 2025
Department of Infectious Diseases, Tata Medical Center, Kolkata, West Bengal, India.
Objective: Catheter-related bloodstream infections (CRBSI) or central line-associated bloodstream infections (CLABSI) occur frequently with long-term indwelling catheters. EDTA (Ethylenediaminetetraacetic acid) and other catheter lock solutions can prevent CRBSI/CLABSI. This study aimed to identify the role of EDTA lock solution in preventing CRBSI/CLABSI compared to the non-EDTA lock solutions.
View Article and Find Full Text PDFA case of yogurt central line-associated bloodstream infection in a child with intestinal failure.
Nutr Clin Pract
August 2025
Section of Gastroenterology, Hepatology & Nutrition, Comer Children's Hospital, University of Chicago, Chicago, Illinois, USA.
Central line-associated bloodstream infections (CLABSI) are a significant cause of morbidity in children with intestinal failure (IF). Probiotic therapy is discouraged in patients with IF because of the increased risk of bacteremia with the probiotic organism. We report an unusual, previously undescribed, clinical presentation of a Lactobacillus-species CLABSI linked to yogurt consumption in a toddler with IF secondary to Megacystis-microcolon-intestinal hypoperistalsis syndrome.
View Article and Find Full Text PDFEarly screening of central line-associated bloodstream infections: A novel comparative analysis of AISI, SII, and SIRI as predictive biomarkers.
Am J Infect Control
August 2025
Department of Microbiology, All India Institute of Medical Sciences, Patna, Bihar, India, 801507. Electronic address:
Purpose: Central line-associated bloodstream infections (CLABSI) are a significant cause of morbidity in critically ill patients. Early detection remains a challenge, as conventional diagnostic markers often fail to capture subtle changes. This study aimed to evaluate the predictive value of inflammatory indices, Aggregate Index of Systemic Inflammation (AISI), Systemic Inflammatory Index (SII) and Systemic Inflammatory Response Index (SIRI), within 2 calendar days of central line insertion.
View Article and Find Full Text PDFPrevalence, Microbiological Profile, and Risk Factors of Healthcare-Associated Infections in Intensive Care Units: A Retrospective Study in Aljouf, Saudi Arabia.
Microorganisms
August 2025
Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi Arabia.
Hospital infection prevention is critical to patient safety, yet data on the prevalence and contributing factors of healthcare-associated infections (HAIs) in Aljouf, Saudi Arabia, are scarce. This retrospective cross-sectional study aimed to investigate the prevalence, microbiological profile, and associated risk factors of HAIs among intensive care unit (ICU) patients in a referral hospital between January 2020 and December 2023. Medical records of 260 ICU patients were reviewed for demographic details, comorbidities, infection types, pathogens, and invasive device use.
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