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Gaps in care across the cancer screening continuum for cervical, colorectal and lung cancer.
J Natl Cancer Inst
September 2025
Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.
Background: While screening for cervical, colorectal, and lung cancers reduce cancer-specific mortality, the full benefits of screening are only realized when coupled with timely care across the subsequent "screening continuum" steps, including surveillance (results warranting frequent monitoring), diagnostic evaluation (results that require additional testing), and treatment (detected cancers). Our goal was to describe the proportion of individuals receiving timely cervical, colorectal, and lung cancer care at each step in the screening continuum.
Methods: This retrospective cohort study used data from the 10 health care settings that participate in the Population-based Research to Optimize the Screening Process (PROSPR II) consortium and included individuals who were eligible for a step along the cancer screening continuum in 2018.
HPV knowledge and non-adherence to cervical cancer screening before and following the COVID-19 pandemic in the United States.
PLOS Glob Public Health
September 2025
Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, United States of America.
To compare HPV vaccination knowledge and non-adherence rates to cervical cancer screening in a nationally representative sample of American women before and following the COVID-19 pandemic, female participants aged 21-65 years from the National Cancer Institute Health Information National Trends Survey 2019 and 2022 were included. Adherence to cervical cancer screening was assessed based on the timing of their last Papanicolaou (PAP) smear, with participants classified as non-adherent to cervical cancer guidelines if their last PAP smear was > 3 years. Further, participants were asked about their knowledge of the HPV vaccine and were categorized as unaware if they had not heard of it before.
View Article and Find Full Text PDFApproaches to address common barriers to colorectal cancer screening in rural communities of the CDC's colorectal cancer control program.
Prev Oncol Epidemiol
May 2025
Implenomics, Dover, DE, USA.
Introduction: We identified potential approaches to address barriers to colorectal cancer (CRC) screening in rural communities of award recipients from the Centers for Disease Control and Prevention's Colorectal Cancer Control Program (CRCCP).
Methods: Nine program managers and directors discussed approaches to address barriers to CRC screening. The programs served areas with rural communities and tribal reservations.
Understanding measles infection and how to improve uptake of the MMR vaccine.
Nurs Child Young People
September 2025
Vaccine Preventable Disease Programme, Public Health Wales, Cardiff, Wales.
Measles is a highly infectious, notifiable, viral disease that is commonly contracted in childhood and associated with a characteristic rash. Most children and young people who contract measles make a full recovery, but measles infection is associated with rare but serious complications in vulnerable groups, such young infants, immunocompromised individuals and pregnant women. Vaccination is the most effective way to prevent measles infection, but uptake of the measles, mumps and rubella (MMR) vaccine in the UK has fallen short of the vaccine coverage required to provide herd immunity and prevent measles outbreaks.
View Article and Find Full Text PDFSilencing CD151 Gene in Donor Triple-Negative Breast Cancer Cells Attenuates Exosome-Driven Functions of Recipient Cells.
Exp Cell Res
September 2025
Cancer Biology Laboratory, Dept of Life Sciences, GITAM School of Sciences, GITAM (Deemed to be University), Visakhapatnam-530045, Andhra Pradesh, India. Electronic address:
CD151 is a tetraspanin, abnormally expressed in triple negative breast cancer (TNBC). It is a prominent component of exosomes, facilitating the secretion of proteins that promote metastasis and drug resistance. We have previously demonstrated that silencing the CD151 gene reduces metastasis in TNBC.
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