Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
If structure dictates function within the living human brain, then the persistence of specific responses to weak electric currents in fixed, deceased brains could reflect "hardwired" properties. Different key structures from the left and right hemispheres of brains that had been fixed for over 20years with ethanol-formalin-acetic acid were stimulated with either 1-Hz, 7-Hz, 10-Hz, 20-Hz, or 30-Hz, sine-wave, square-wave, or pulsed currents while needle-recorded quantitative electroencephalographic responses were obtained. Differential responses occurred only within the right hippocampus and parahippocampal gyrus. The right hippocampus displayed frequency-independent increases in gamma power relative to the left hemispheric homologue. The parahippocampal region responded exclusively to 7-Hz pulsed currents with wideband (8-30Hz) power. These profiles are consistent with dynamic connections associated with memory and consciousness and may partially explain the interactions resultant of pulse type and hemisphere for experiential elicitations during the golden age of surgical stimulations. The results also indicate that there may be an essential "hardwiring" within the human brain that is maintained for decades when it is fixed appropriately.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.yebeh.2016.04.028 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Neural tracking of social navigation in autism spectrum disorder.
Biol Psychiatry
September 2025
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029 USA; Center for Computational Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10027 USA; The Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029 USA; Nash Fami
Background: As we navigate changing social landscapes, maintaining maps of interpersonal dynamics can help guide our choices. Autism spectrum disorder (ASD) is associated with social challenges that may affect the accumulation or application of social information. However, little is known about social cognitive mapping in autistic adults.
View Article and Find Full Text PDFMRI Assessment of Radiation-Induced Delayed-Onset Microstructural Gray Matter Changes in Nasopharyngeal Carcinoma Patients.
J Magn Reson Imaging
September 2025
School of Biomedical Engineering, Guangdong Provincial Key Laboratory of Medical Image Processing and Guangdong Province Engineering Laboratory for Medical Imaging and Diagnostic Technology, Southern Medical University, Guangzhou, China.
Background: The dynamic progression of gray matter (GM) microstructural alterations following radiotherapy (RT) in patients, and the relationship between these microstructural abnormalities and cortical morphometric changes remains unclear.
Purpose: To longitudinally characterize RT-related GM microstructural changes and assess their potential causal links with classic morphometric alterations in patients with nasopharyngeal carcinoma (NPC).
Study Type: Prospective, longitudinal.
Structural and functional neural correlates of sensorimotor deficits in progression of hepatic encephalopathy.
Magn Reson Lett
May 2025
Department of Medical Imaging, Tianjin First Central Hospital, Tianjin, 300192, China.
Hepatic encephalopathy (HE) is a neurological condition that occurs as a complication of liver dysfunction that involves sensorimotor symptoms in addition to cognitive and behavioral changes, particularly in cases of severe liver disease or cirrhosis. Previous studies have reported spatially distributed structural and functional abnormalities related to HE, but the exact relationship between the structural and functional alterations with respect to disease progression remains unclear. In this study, we performed surface-based cortical thickness comparisons and functional connectivity (FC) analyses between three cross-sectional groups: healthy controls (HC, = 51), patients with minimal hepatic encephalopathy (MHE, = 50), patients with overt hepatic encephalopathy (OHE, = 51).
View Article and Find Full Text PDFDifferential effects of obesity and hypertension on brain structure and cognitive ability: A subgroup analysis from nested study.
J Educ Health Promot
July 2025
Department of Medical Imaging Technology, Manipal College of Health Professions Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Background: Obesity and hypertension are widespread health issues associated with changes in brain structure and cognitive function, especially in individuals who lead sedentary lifestyles. This research examines the connections between obesity, high blood pressure, brain structure, and cognitive abilities in people who lead a sedentary lifestyle.
Materials And Methods: The study involved 90 individuals aged between 18 and 35 years, who were categorized into three groups: control (n = 30), obese (n = 30), and hypertensive (n = 30).
[Study of Successful Emotional Memory Encoding with Functional Magnetic Resonance Imaging: A Meta-Analysis Comparing the Affective Salience of Words Versus Images].
Rev Neurol
August 2025
Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229-3900, USA.
Background: Functional magnetic resonance imaging (fMRI) studies examining emotional memory encoding often use event-related designs with stimuli in the form of words or pictures. Prior research has suggested differential hemispheric specialization for these stimulus types, yet no meta-analysis has directly compared the neural systems involved in each.
Methods: A meta-analysis was conducted using peer-reviewed, event-related fMRI studies.