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The NHS has undertaken research on the organisation and quality of end-of-life services, which provides valuable insights for those planning and delivering care for people approaching the end of life, and their families. The review of the findings, structured around the right care in the right place at the right time, highlights what is already known, and how research that is currently underway will address key gaps and uncertainties for frontline staff and clinical leaders. This article summarises the findings outlined in that review.
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JAMA Netw Open
September 2025
Department of Urology, Center for Health Outcomes Research and Dissemination, University of Washington, Seattle.
Importance: Black individuals have a twofold higher rate of prostate cancer death in the US compared with the average population with prostate cancer. Few guidelines support race-conscious screening practices among at-risk Black individuals.
Objective: To examine structural factors that facilitate or impede access to prostate cancer screening among Black individuals in the US.
Am J Forensic Med Pathol
September 2025
Forensic Pathology and Coronial Services, Pathology Queensland, Queensland Health.
Predation by domestic pigs is unusual but not unheard of. However, predation by a herd of pigs is rare and has not been previously reported in the literature. We present a case report of an individual with predation by a herd of domestic pigs.
View Article and Find Full Text PDFPediatr Crit Care Med
September 2025
Department of Cardiac, Respiratory and Critical Care, Evelina London Children's Hospital, London, United Kingdom.
Objectives: To identify factors associated with death, requirement for extracorporeal membrane oxygenation (ECMO), or cardiac intervention in neonates referred for higher level neonatal ICU (NICU) due to respiratory failure.
Design: Retrospective cohort study, 2018-2020.
Setting: Referrals for transport to tertiary-level NICUs using the London Neonatal Transfer Service in the United Kingdom.
J Biochem Mol Toxicol
September 2025
Department of Anesthesiology, Qianjiang Maternal and Child Health and Family Planning Service Centre, Qianjiang, Hubei, China.
Acute lung injury (ALI) is a major contributor to the high morbidity and mortality associated with intestinal ischemia-reperfusion (II/R). Despite its severity, current clinical management of ALI remains limited to supportive care without addressing the cause of the disease, underscoring the urgent need to investigate the underlying mechanism and develop targeted therapies. In this study, we employed both in vitro and in vivo models to explore ALI in the setting of II/R.
View Article and Find Full Text PDFClin Exp Dent Res
October 2025
Tasmanian School of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Tasmania, Australia.
Objectives: Oral health is an important aspect of quality of life for older people, especially those with dementia. The impact of an active oral hygiene program on the oral microbiome was explored in a group of older participants (average age 84 years old) with dementia against a separate control group whose oral hygiene followed the status quo.
Materials And Methods: The oral cavity bacteriomes and mycobiomes were assessed from swabs of cheek, gum, and tongue surfaces.