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Idiopathic myointimal hyperplasia of mesenteric veins (IMHMV) is a rare condition of the rectosigmoid colon that primarily affects middle-aged men. IMHMV typically presents as proctosigmoiditis and often requires surgical resection due to complications throughout the protracted clinical course. It can be differentiated from idiopathic chronic inflammatory bowel disease by histopathologic examination of surgically resected colon specimens. This report describes a rare case of IMHMV presenting as left hemicolitis in a 64-year-old male. We also describe potentially distinguishing computed tomographic and angiographic findings that may aid in the diagnosis of IMHMV.
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http://dx.doi.org/10.1016/j.clinimag.2015.12.017 | DOI Listing |
Med Clin (Barc)
June 2025
Central Laboratory, The Affiliated Panyu Central Hospital, Guangzhou Medical University, Guangzhou, China. Electronic address:
Objective: Enterocolic lymphocytic phlebitis (ELP) is a rare venous-specific gastrointestinal inflammation with challenging preoperative diagnosis. We aimed to characterize its clinicopathological spectrum.
Patients And Methods: This narrative review synthesizes evidence from 85 published cases (9-81 years) from 50 articles to characterize ELP's clinicopathological features and diagnostic pitfalls, along with its differentiation from other vasculitides, such as Behcet's disease, systemic lupus erythematosus, mesenteric inflammatory veno-occlusive disease, idiopathic myointimal hyperplasia of the mesenteric veins and IgG4-related diseases.
Surg Case Rep
June 2025
Department of Gastrointestinal Surgery, Yokohama Municipal Citizen's Hospital, Yokohama, Kanagawa, Japan.
Introduction: Idiopathic myointimal hyperplasia of the mesenteric veins (IMHMV) is a rare, non-thrombotic ischemic bowel disease caused by the proliferation of smooth muscle cells in the venous intima. Most patients are initially diagnosed with typical ischemic colitis or inflammatory bowel disease (IBD) and are treated nonsurgically. There is no established treatment for IMHMV, and surgery is the mainstay of treatment, although the optimal surgical approach remains unclear.
View Article and Find Full Text PDFWorld J Gastroenterol
May 2025
Department of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan Province, China.
Background: Idiopathic myointimal hyperplasia of the mesenteric veins (IMHMV) is a rare disease characterized by narrowing of the lumen caused by mesenteric vein intimal hyperplasia, resulting in chronic intestinal ischemia. Although the colorectum is the primary site affected by this condition, involvement of the small intestine is even more rare. Recurrence of IMHMV after surgical resection of the affected bowel is uncommon.
View Article and Find Full Text PDFCureus
March 2025
Endoscopy, Hospital Moriah, São Paulo, BRA.
Idiopathic myointimal hyperplasia of the mesenteric veins (IMHMV) is a rare cause of segmental intestinal ischemia. It is usually associated with chronic symptoms of abdominal pain, diarrhea, and rectal bleeding, but it also can present in more acute and dramatic clinical presentations. Surgical segmental bowel resection is the proper treatment, but it is commonly delayed by the misdiagnosis of this condition as inflammatory bowel disease, such as Crohn's or idiopathic ulcerative colitis.
View Article and Find Full Text PDFTher Drug Monit
April 2025
Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Background: We report a case of a 19-year-old man with severe total parenteral nutrition-dependent protein-losing enteropathy who was treated with upadacitinib. Treatment was complicated by renal failure requiring hemodialysis and severe diarrhea, which possibly hindered absorption.
Methods: Therapeutic drug monitoring (TDM) and pharmacokinetic analyses were compared with published population pharmacokinetic data to determine the dose adjustments for each patient.