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Introduction: Femtosecond Laser-assisted cataract surgery represents a modern technology that hopes to lower the risk of complications for patients suffering from Fuchs endothelial dystrophy by using a reduced level of energy that causes less damage to the endothelium, the main concern for patients with Fuchs endothelial dystrophy. The femtosecond laser performs 3 important steps in cataract surgery: corneal incisions, capsulorhexis and nucleus fragmentation without intraocular instrument manipulation.
Purpose: The purpose of this study is to determine the efficiency of Femtosecond Laser-assisted cataract surgery in Fuchs endothelial dystrophy.
Material And Methods: 5 patients with 6 eyes underwent cataract surgery assisted by Femtosecond Laser LensX at Laser Optisan Clinic. Corneal changes before and after surgery and cumulative dissipated energy (CDE) were analyzed.
Results: Before surgery, our patients presented BCVA between 0.16-0.4, Pachymetry between 450-590 Lm, endothelial cells between 789-2008 mm2. The medium cumulative dissipated energy (CDE) used was 4.58 seconds. After surgery, BCVA improved in all patients and none of them developed corneal decompensation so far.
Conclusions: Femtosecond Laser-assisted cataract surgery represents a safe alternative in patients with Fuchs endothelial dystrophy and has a low risk of corneal decompensation.
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Exp Eye Res
September 2025
Cornea, Cataract and Refractive Surgery Unit, Vissum (Miranza Group), Alicante, Spain; Division of Ophthalmology, School of Medicine, Universidad Miguel Hernández, Alicante, Spain. Electronic address:
Corneal opacity remains a leading cause of global blindness, yet conventional corneal transplantation is constrained by donor scarcity, surgical limitations, and suboptimal long-term outcomes. In response, regenerative strategies are advancing to restore structural and functional integrity across all three corneal layers-epithelium, stroma, and endothelium-through cell-based and bioengineered therapies. Among these, induced pluripotent stem cells (iPSCs) have emerged as a versatile and scalable source capable of generating corneal-like cells under defined, xeno-free conditions.
View Article and Find Full Text PDFJ Cataract Refract Surg
September 2025
Ophthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.
Purpose: To compare the usability and training effectiveness of a 3D-printed coaxial illumination system mounted on an off-the-shelf stereo-microscope to a professional ophthalmic surgical microscope, in cataract surgery simulation.
Setting: Ophthalmology Lab, Ophthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.
Design: Prospective randomized crossover study.
J Cataract Refract Surg
July 2025
Department of Ophthalmology, Saarland University Medical Center, Homburg/Saar, Germany.
Topic: The aim of this study was to assess the meta-analysis of the studies comparing transepithelial photorefractive keratectomy (TransPRK) to classical photorefractive keratectomy (PRK) (mechanical or alcohol-assisted).
Clinical Relevance: While PRK is a well-established procedure, TransPRK, a newer, minimally invasive technique may reduce surgery time and improve patient outcomes. Comparing these techniques helps optimize surgical choices.
J Cataract Refract Surg
July 2025
Helsinki Retina Research Group, University of Helsinki, Finland.
Topic: To compare the outcomes of surgical approaches to correct ametropia following cataract and lens surgery.
Clinical Relevance: Despite advancements in the field of biometry and intraocular lens (IOL) power calculation formulas, complete elimination of refractive surprises following cataract and lens surgery is impossible. Preferred Practice Patterns acknowledges the possibility of refractive surprise following cataract surgery; however, no recommendations regarding the preferred treatment have been given.
Pol Merkur Lekarski
September 2025
BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE.
Objective: Aim: To evaluate the possibility of using cataract phacoemulsification with simultaneous intraocular lens (IOL) implantation in patients with age-related cataract (ARC) combined with pseudoexfoliation syndrome (PES) as an algorithm for the pseudoexfoliation glaucoma (PEG) prevention..
Patients And Methods: Materials and Methods: A retrospective case-control study was conducted using data from medical records of 610 outpatients (813 eyes) with ARC aged from 49 to 79 years (average age 69 ± 3 years).