Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Nipple-sparing mastectomy (NSM) is a recognized treatment for selected patients with breast cancer (BC). Our study aimed to analyze 7 years' experience in NSM and breast reconstruction for patients with preoperative diagnosis of non-invasive BC.
Patients And Methods: All NSMs with breast reconstruction, performed between January 2007 and December 2013 in patients with preoperative diagnosis of non-invasive BC, were considered.
Results: Thirty-five NSMs were performed, 23 cases confirming the diagnosis of non-invasive BC, and in 12 patients it also resulted in findings of an invasive component. Patients were stratified into two groups: breast reconstruction was performed i) with silicone definitive implant, ii) with a temporary breast tissue expander. An invasive component at the postoperative histological examination was significantly associated with tissue expander reconstruction (p=0.03).
Conclusion: In selected cases, NSM is a valid and safe procedure. Further critical evaluations are required for more evidence on this argument.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Luminescent Electro-Spun Nanofibers Crosslinked with Boronic Esters Exhibiting Controlled Release of Carbon Dots for Detection of Wound pHs and Enhanced Antimicrobial.
Macromol Biosci
September 2025
Department of Chemistry and Biochemistry, Concordia University, Montreal, Quebec, Canada.
Timely and accurate assessment of wounds during the healing process is crucial for proper diagnosis and treatment. Conventional wound dressings lack both real-time monitoring capabilities and active therapeutic functionalities, limiting their effectiveness in dynamic wound environments. Herein, we report our proof-of-concept approach exploring the unique emission properties and antimicrobial activities of carbon nanodots (CNDs) for simultaneous detection and treatment of bacteria.
View Article and Find Full Text PDFReduced Predictive Performance of the FIB-4 Index in Chronic Hepatitis B Patients With Concurrent Metabolic Dysfunction-Associated Liver Disease.
J Viral Hepat
October 2025
Technion Israel Institute of Technology, Rappaport Faculty of Medicine, Haifa, Israel.
The coexistence of chronic hepatitis B (CHB) and metabolic dysfunction-associated liver disease (MASLD) gained recognition, but the diagnostic performance of non-invasive markers regarding it remains underexplored. This study aimed to evaluate the utility of the FIB-4 index for fibrosis prediction in CHB patients and investigate its performance in the distinct subgroup of CHB-MASLD. A prospective study from 2021 to 2022 included 109 CHB and 64 CHB-MASLD patients.
View Article and Find Full Text PDFAims: Many patients develop Fontan-associated liver disease (FALD) after undergoing the Fontan procedure-a surgical treatment for congenital heart disease such as single ventricle-owing to changes in venous pressure and cardiac output. Liver biopsy is the gold standard for diagnosing FALD, but has limitations. Magnetic resonance elastography (MRE) is a popular non-invasive method for evaluating liver stiffness and fibrosis in FALD; however, no unified view exists.
View Article and Find Full Text PDFInvolvement of lncRNA in cancer diagnosis and prognosis and clinical implications.
Rep Pract Oncol Radiother
August 2025
Department of Biosciences, Manipal University Jaipur, Dehmi Kalan, Jaipur, Rajasthan, India.
Long non-coding ribonucleic acids (lncRNAs) form a subclass of non-coding RNAs (ncRNAs), they are quite long and as their name non-coding suggests they do not have a role in protein coding. lncRNAs are vital in all the key steps of tumorigenesis, such as epithelial-mesenchymal transition, cancer stem cells formation, invasion, migration, and formation of the tumor vasculature. lncRNAs are classified into oncogenic or anti-tumor lncRNAs based on their functions.
View Article and Find Full Text PDFLiquid biopsy- A pivotal test to help navigate clinical decisions at a precision center in India!
J Liq Biopsy
September 2025
Datar Cancer Genetics, Nashik, Maharashtra, India.
Liquid biopsy, specifically circulating tumor DNA (ctDNA) analysis, has emerged as a transformative tool in precision oncology, providing real-time, minimally invasive characterizations of the tumor and tumor dynamics. While tissue biopsy is a critical tool for baseline diagnosis of malignancy, it is often limited by sampling constraints and an inability to capture tumor heterogeneity. In this study, we explored the clinical utility of serial ctDNA testing in guiding therapeutic decisions across a cohort of 30 patients with diverse solid tumors.
View Article and Find Full Text PDF