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Objective: Personal health applications have the potential to help patients with chronic disease by improving medication adherence, self-efficacy, and quality of life. The goal of this study was to assess the impact of MyMediHealth (MMH) - a website and a short messaging service (SMS)-based reminder system - on medication adherence and perceived self-efficacy in adolescents with asthma.
Methods: We conducted a block-randomized controlled study in academic pediatric outpatient settings. There were 98 adolescents enrolled. Subjects who were randomized to use MMH were asked to create a medication schedule and receive SMS reminders at designated medication administration times for 3 weeks. Control subjects received action lists as a part of their usual care. Primary outcome measures included MMH usage patterns and self-reports of system usability, medication adherence, asthma control, self-efficacy, and quality of life.
Results: Eighty-nine subjects completed the study, of whom 46 were randomized to the intervention arm. Compared to controls, we found improvements in self-reported medication adherence (P = .011), quality of life (P = .037), and self-efficacy (P = .016). Subjects reported high satisfaction with MMH; however, the level of system usage varied widely, with lower use among African American patients.
Conclusions: MMH was associated with improved medication adherence, perceived quality of life, and self-efficacy.Trial Registration This project was registered under http://clinicaltrials.gov/ identifier NCT01730235.
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http://dx.doi.org/10.1093/jamia/ocv158 | DOI Listing |
JNCI Cancer Spectr
September 2025
Pennington Biomedical Research Center, Baton Rouge, LA 70808, United States.
Background: Cancer survivors may be more likely to experience accelerated declines in physical function compared to cancer-free controls, but objective data and knowledge of preventive interventions are limited.
Methods: The Lifestyle Interventions and Independence for Elders (LIFE) study was a multicenter, single-blinded, randomized trial conducted at 8 centers across the United States that enrolled 1635 sedentary adults aged 70-89 years and with physical limitations but who could walk 400 m at baseline, of which 371 (22.7%) reported a history of cancer.
Health Serv Res
September 2025
Nova Southeastern University, Department of Psychology & Neuroscience, Fort Lauderdale, USA.
Objective: To examine the impact of patient-provider racial/ethnic concordance on adherence to a prescribed medication regimen in marginalized populations with a focus on health issues related to hypertension, heart condition/disease, elevated cholesterol, and diabetes.
Study Setting And Design: Applying the Andersen-Newman Behavioral Model of Health Service Use, we estimate multivariate linear models to analyze the number of prescriptions filled by patients within a calendar year using publicly available data from the Medical Expenditure Panel Survey (MEPS), a set of large-scale surveys of families and individuals, their medical providers, and employers across the United States.
Data Sources And Analytic Sample: Data from MEPS on patient race/ethnicity and provider race/ethnicity were collected from survey years 2007 to 2017 as well as data to control for demographic, socioeconomic, and health factors.
J Bras Pneumol
September 2025
. Departamento de Pneumologia do Hospital Infante D. Pedro, Unidade Local de Saúde da Região de Aveiro, Aveiro, Portugal.
Objectives: This study explores the relationship between inhaler visual identification, naming, and adherence outcomes, and evaluates the potential of combining these factors into a screening tool for identifying poor adherence.
Methods: This observational, prospective study included adult patients with COPD, asthma, or asthma+COPD who had been on chronic inhalation therapy for at least the past year. Data were collected through patient interviews and medical records.
Arq Gastroenterol
September 2025
Universidade Federal da Bahia, Faculdade de Medicina, Programa de Pós-graduação em Medicina e Saúde, Salvador, BA. Brasil.
Objective: Identify psychosocial risk factors for non-adherence to medication following liver transplantation.
Methods: We used the Medication Level Variability Index (MLVI) for the assessment of adherence in 52 subjects selected for a pre-transplant liver procedure and monitored them for 6 months following transplantation. Patients were divided into exposed and non-exposed groups according to adherence, and each group was analyzed using psychosocial variables: demographic characteristics, quality of life, impulsivity, resilience, anxiety and depression.
J Multidiscip Healthc
September 2025
School Public Health and Social Work, Faculty of Health, Queensland University of Technology, Brisbane, QLD, Australia.
Background: Diabetes mellitus is a major health challenge among older adults in Asia. Challenges include limited healthcare access and poor self-care adherence. Continuity of care has emerged as a key strategy to enhance diabetes self-management in this population.
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