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Purpose: Assistance algorithms for medical tasks have great potential to support physicians with their daily work. However, medicine is also one of the most demanding domains for computer-based support systems, since medical assistance tasks are complex and the practical experience of the physician is crucial. Recent developments in the area of cognitive computing appear to be well suited to tackle medicine as an application domain.
Methods: We propose a system based on the idea of cognitive computing and consisting of auto-configurable medical assistance algorithms and their self-adapting combination. The system enables automatic execution of new algorithms, given they are made available as Medical Cognitive Apps and are registered in a central semantic repository. Learning components can be added to the system to optimize the results in the cases when numerous Medical Cognitive Apps are available for the same task. Our prototypical implementation is applied to the areas of surgical phase recognition based on sensor data and image progressing for tumor progression mappings.
Results: Our results suggest that such assistance algorithms can be automatically configured in execution pipelines, candidate results can be automatically scored and combined, and the system can learn from experience. Furthermore, our evaluation shows that the Medical Cognitive Apps are providing the correct results as they did for local execution and run in a reasonable amount of time.
Conclusion: The proposed solution is applicable to a variety of medical use cases and effectively supports the automated and self-adaptive configuration of cognitive pipelines based on medical interpretation algorithms.
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http://dx.doi.org/10.1007/s11548-015-1322-y | DOI Listing |
PLoS One
September 2025
School of Computer Science, Georgia Institute of Technology, Atlanta, Georgia, United States of America.
Background: When analyzing cells in culture, assessing cell morphology (shape), confluency (density), and growth patterns are necessary for understanding cell health. These parameters are generally obtained by a skilled biologist inspecting light microscope images, but this can become very laborious for high-throughput applications. One way to speed up this process is by automating cell segmentation.
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September 2025
Korea University College of Medicine, Seoul, Republic of Korea.
Purpose: To develop and validate a deep learning-based model for automated evaluation of mammography phantom images, with the goal of improving inter-radiologist agreement and enhancing the efficiency of quality control within South Korea's national accreditation system.
Materials And Methods: A total of 5,917 mammography phantom images were collected from the Korea Institute for Accreditation of Medical Imaging (KIAMI). After preprocessing, 5,813 images (98.
PLoS One
September 2025
School of Medical Engineering, Xinxiang Medical University, Xinxiang, China.
Computer-aided diagnostic (CAD) systems for color fundus images play a critical role in the early detection of fundus diseases, including diabetes, hypertension, and cerebrovascular disorders. Although deep learning has substantially advanced automatic segmentation techniques in this field, several challenges persist, such as limited labeled datasets, significant structural variations in blood vessels, and persistent dataset discrepancies, which continue to hinder progress. These challenges lead to inconsistent segmentation performance, particularly for small vessels and branch regions.
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September 2025
School of Computer Science and Engineering, Southeast University, China.
Metaheuristic optimization algorithms often face challenges such as complex modeling, limited adaptability, and a tendency to get trapped in local optima when solving complex optimization problems. To enhance algorithm performance, this paper proposes an enhanced Secretary Bird Optimization Algorithm (MESBOA) based on a precise elimination mechanism and boundary control. The algorithm integrates three key strategies: a precise population elimination strategy, which optimizes the population structure by eliminating individuals with low fitness and intelligently generating new ones; a lens imaging-based opposition learning strategy, which expands the exploration of the solution space through reflection and scaling to reduce the risk of local optima; and a boundary control strategy based on the best individual, which effectively constrains the search range to avoid inefficient searches and premature convergence.
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September 2025
Department of Pathology, Hospital Tuanku Fauziah, Jalan Tun Abdul Razak, Kangar, Perlis, Malaysia.
Cervical cancer remains a significant cause of female mortality worldwide, primarily due to abnormal cell growth in the cervix. This study proposes an automated classification method to enhance detection accuracy and efficiency, addressing contrast and noise issues in traditional diagnostic approaches. The impact of image enhancement on classification performance is evaluated by comparing transfer learning-based Convolutional Neural Network (CNN) models trained on both original and enhanced images.
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