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http://dx.doi.org/10.1111/cobi.12666 | DOI Listing |
Langenbecks Arch Surg
September 2025
Department of Surgery (A), Medical Faculty, Heinrich-Heine-University, University Hospital Duesseldorf, Duesseldorf, Germany.
Introduction: Remote ischaemic preconditioning (RIPC) which consists of repeated brief episodes of non-lethal limb ischaemia is associated with organ protection and improved clinical outcomes through complex pathophysiological pathways. The aim of this meta-analysis was to evaluate the postoperative effects of RIPC in bowel recovery and surgical morbidity after colorectal surgery.
Methods: In strict adherence to the PRISMA guidelines, a systematic literature search was performed for studies comparing the postoperative effect RIPC in colorectal surgery.
Elife
September 2025
Chinese Academy of Medical Science Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Influenza virus neuraminidase (NA) is a crucial target for protective antibodies, yet the development of recombinant NA protein as a vaccine has been held back by instability and variable expression. We have taken a pragmatic approach to improving expression and stability of NA by grafting antigenic surface loops from low-expressing NA proteins onto the scaffold of high-expressing counterparts. The resulting hybrid proteins retained the antigenic properties of the loop donor while benefiting from the high-yield expression, stability, and tetrameric structure of the loop recipient.
View Article and Find Full Text PDFPest Manag Sci
September 2025
Department of Horticulture, Oregon State University, Corvallis, OR, USA.
Background: Herbicide resistance evolution is a major challenge in agriculture. Poa annua L., a globally distributed and genetically diverse weed, has repeatedly evolved resistance to multiple herbicide sites of action due to its genetic plasticity and rapid life cycle.
View Article and Find Full Text PDFDrug Res (Stuttg)
September 2025
Department of Pharmacology and Toxicology, School of Pharmacy, Ardabil University of Medical Sciences, Ardabil, Iran.
We investigated, in vivo, the chemopreventive efficacy of sinapic acid, as a known radical scavenger and antioxidant on mortality and toxicity in a N-ethyl-N-nitrosourea (ENU)-induced chronic lymphocytic leukemia (CLL) model in mice.Mice were divided into three groups: control (normal saline), ENU (80 mg/kg, i.p.
View Article and Find Full Text PDFFront Microbiol
August 2025
School of Life Sciences, Ludong University, Yantai, China.
Background: Feline panleukopenia, caused by the highly lethal feline parvovirus (FPV), lacks effective prevention and treatment strategies. This study aimed to elucidate the key metabolic regulatory mechanisms during FPV infection.
Methods: CRFK cells were infected with the FPV013 strain.