Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
A new approach to trap air bubbles before they enter microfluidic systems is presented. The bubble trap is based on the combined interaction of surface tension and hydrodynamic forces. The design is simple, easy to fabricate and straightforward to use. The trap is made of tubes of different sizes and can easily be integrated into any microfluidic setup. We describe the general working principle and derive a simple theoretical model to explain the trapping. Furthermore, the natural oscillations of trapped air bubbles created in this system are explained and quantified in terms of bubble displacement over time and oscillation frequency. These oscillations may be exploited as a basis for fluidic oscillators in future microfluidic systems.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c5lc00592b | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Integrating microfluidic automation into thermoplastic devices for analysis of small volumes of blood.
Biosens Bioelectron
December 2025
Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA. Electronic address:
Microfluidic devices with built-in microvalves hold particular promise for minimizing sample volume requirements while automating sample preparation workflows. Such devices have typically been implemented in polydimethyl siloxane (PDMS) using multi-layer soft lithography. Both the material and assembly process of devices present challenges for scalable manufacturing and limit utilization of microfluidic automation at the point of care.
View Article and Find Full Text PDFAtomistic Mechanisms and Temperature-Dependent Criteria of Trap Mutation in Vacancy-Helium Clusters in Tungsten.
Materials (Basel)
July 2025
College of Science, Jinling Institute of Technology, Nanjing 211169, China.
Helium (He) accumulation in tungsten-widely used as a plasma-facing material in fusion reactors-can lead to clustering, trap mutation, and eventual formation of helium bubbles, critically impacting material performance. To clarify the atomic-scale mechanisms governing this process, we conducted systematic molecular statics and molecular dynamics simulations across a wide range of vacancy cluster sizes (n = 1-27) and temperatures (500-2000 K). We identified the onset of trap mutation through abrupt increases in tungsten atomic displacement.
View Article and Find Full Text PDFLaser-Induced Trapping of Microbubbles within the Bulk Solution.
Langmuir
July 2025
Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, Indiana 46556, United States.
The generation and manipulation of microbubbles on surfaces have been much more ubiquitous than those in the bulk liquid. In this paper, we report the generation and trapping of microbubbles at the laser boundary in the bulk of water. In a plasmonic suspension, the light intensity-induced temperature gradient leads to a Marangoni flow that can trap the microbubble.
View Article and Find Full Text PDFOrientation-independent bubble trap with internal partition for robust operation of microfluidic systems.
Lab Chip
July 2025
San Jose State University, San Jose, California, USA.
A new monolithic bubble trap has been developed with a unique, orientation-independent design. The bubble trap has a spherical cavity and a central partition with internal passages that eliminate air bubbles effectively for extended periods of time. Flow testing was performed in a closed-loop microfluidic system to demonstrate effectiveness and robustness of the bubble trap.
View Article and Find Full Text PDFIonized Calcium Before Venous Bubble Trap Strongly Affects Coagulation When Using Calcium-Containing Dialysate in Regional Citrate Anticoagulation for Intermittent Hemodialysis: A Real-World Prospective Study.
Ther Apher Dial
October 2025
Department of Nephrology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Introduction: Regional citrate anticoagulation (RCA) is highly recommended as an anticoagulation method for intermittent hemodialysis (IHD) in patients at high bleeding risk. Few studies have investigated the effect of ionized calcium (iCa) concentration at different pipeline points on circuit clotting in RCA using calcium-containing dialysate.
Methods: This prospective study included 185 IHD sessions treated with a two-stage RCA protocol.