Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Purpose: To evaluate the efficacy of surgery with neuronavigation compared to conventional neurosurgical treatment of epilepsy in terms of safety and seizure outcomes and to assess the quality of the evidence base of neuronavigation in this clinical context.
Method: Systematic review using the electronic databases of Cochrane, CRD, PubMed, Embase, SciELO and LILACS in Portuguese, English and Spanish. The [MeSH] terms included "epilepsy" and "neuronavigation".
Eligibility Criteria: Studies assessing surgery with neuronavigation for the surgical treatment of epilepsy or brain injuries associated with epileptic seizures.
Results: We identified 28 original articles. All articles yielded scientific evidence of low quality. Outcome data presented in the articles identified was heterogeneous and did not amount to compelling evidence that epilepsy surgery with neuronavigation produces higher rates of seizure control, a reduced need for reoperations, or lower rates of complications or postoperative neurological deficits.
Conclusion: We were unable to find any publications providing convincing evidence that neuronavigation improves outcomes of epilepsy surgery. Whilst this does not mean that neuronavigation cannot improve neurosurgical outcomes in this clinical setting, well-designed research studies evaluating the role of neuronavigation are urgently needed.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.seizure.2015.07.010 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Intraoperative electrocorticography in focal drug-resistant epilepsy: A 10-year retrospective single-center study.
Biomed Rep
November 2025
Department of Pediatric Neurology, King Fahad Specialist Hospital, Dammam 31444, Saudi Arabia.
Intraoperative electrocorticography (ECoG) represents a crucial tool for improving seizure outcomes during epilepsy surgeries by assisting in localization of the epileptogenic zones. There is a shortage of information in the literature regarding single-center experiences and long-term outcomes after ECoG-guided surgeries. Data are particularly scarce from the Eastern Mediterranean Region.
View Article and Find Full Text PDFPatients with seizure disorders frequently present for anesthetic care, and anesthesiologists must be adequately equipped to manage these patients safely throughout the perioperative period. While Part I of this review focused on seizure diagnosis, classification, and treatment, Part II focuses on perioperative considerations for patients with seizure disorders. A detailed preoperative assessment is imperative as well as an in-depth understanding of the patient's medications and treatment modalities.
View Article and Find Full Text PDFCortical versus hippocampal network dysfunction in a human brain assembloid model of epilepsy and intellectual disability.
Cell Rep
September 2025
Department of Neurology, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA 90095, USA; Department of Neurobiology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Un
Neurodevelopmental disorders often impair multiple cognitive domains. For instance, a genetic epilepsy syndrome might cause seizures due to cortical hyperexcitability and present with memory impairments arising from hippocampal dysfunction. This study examines how a single disorder differentially affects distinct brain regions using induced pluripotent stem cell (iPSC)-derived cortical- and hippocampal-ganglionic eminence assembloids to model developmental and epileptic encephalopathy 13, a condition arising from gain-of-function mutations in the SCN8A gene encoding the sodium channel Nav1.
View Article and Find Full Text PDFThe characteristics of the cases with brain abscess and the analysis of the predictive factors for poor outcome.
J Infect Dev Ctries
August 2025
Department of Infectious Diseases and Clinical Microbiology, Health Sciences University Adana City Training and Research Hospital, Adana, Turkey.
Introduction: To evaluate the characteristics of patients who have undergone surgical operations due to brain abscess and to assess the risk factors for mortality and the outcomes.
Methodology: Patients who have undergone surgical operations due to brain abscess between January 2014 and January 2024 in our hospital were evaluated retrospectively. Patients were divided into 2 groups to determine poor outcome predictive factors.
Preliminary Safety Study of a Single-dose Perampanel Drip Infusion in Brain Tumor Patients to Prevent Early Postoperative Seizures: The poSTOP Seizure-1 SF Study.
Neurol Med Chir (Tokyo)
September 2025
Department of Neurosurgery, Institute of Medicine, University of Tsukuba.
Early postoperative seizures, defined as occurring within 7 days after surgery, are a significant complication that occurs following neurosurgical procedures involving cerebral manipulation. As a result, short-term antiseizure medication is typically administered in Japan despite the lack of consensus regarding its prophylactic use. Perampanel hydrate, an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist, was recently introduced in an intravenous formulation in Japan, providing new potential for early postoperative seizures prevention during the perioperative period.
View Article and Find Full Text PDF