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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137015 | PLOS |
Phys Rev Lett
August 2025
Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 100190, China.
Quantum low-density parity-check (QLDPC) codes offer a promising path to low-overhead fault-tolerant quantum computation but lack systematic strategies for exploration. In this Letter, we establish a topological framework for studying the bivariate-bicycle codes, a prominent class of QLDPC codes tailored for real-world quantum hardware. Our framework enables the investigation of these codes through universal properties of topological orders.
View Article and Find Full Text PDFPLoS Comput Biol
September 2025
Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America.
Fanconi Anemia (FA) is a heritable syndrome characterized by DNA damage repair deficits, frequent malformations and a significantly elevated risk of bone marrow failure, leukemia, and mucosal head and neck squamous cell carcinomas (HNSCC). Hematopoietic stem cell gene therapy can prevent marrow failure and lower leukemia risk, but mucosal gene therapy to lower HNSCC risk remains untested. Major knowledge gaps include an incomplete understanding of how rapidly gene-corrected cellular lineages could spread through the oral epithelium, and which delivery parameters are critical for ensuring efficient gene correction.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
September 2025
Dipartimento di Fisica, Sapienza Università di Roma, Roma 00185, Italy.
We analyze the spin-glass transition in a field in finite dimension [Formula: see text] below the upper critical dimension directly at zero temperature using a recently introduced perturbative loop expansion around the Bethe lattice solution. The expansion is generated by the so-called [Formula: see text]-layer construction, and it has [Formula: see text] as the associated small parameter. Computing analytically and numerically these nonstandard diagrams at first order in the [Formula: see text] expansion, we construct an [Formula: see text]-expansion around the upper critical dimension [Formula: see text], with [Formula: see text].
View Article and Find Full Text PDFRev Med Suisse
August 2025
Unité de nutrition clinique, Service de gastroentérologie et hépatologie, Hôpitaux universitaires de Genève, 1211 Genève 14.
Refeeding syndrome (RFS), which is often underdiagnosed, is a preventable condition that can be fatal if not managed early. It may occur after nutrition is reintroduced in malnourished patients or those who have experienced a prolonged reduction in food intake. As a result of the metabolic shift from a catabolic to an anabolic state, RFS is characterized by electrolyte disturbances and vitamin deficiencies, which can lead to severe clinical complications.
View Article and Find Full Text PDFRev Sci Instrum
September 2025
LAPLACE, Université de Toulouse, CNRS, INPT, UPS, 118 route de Narbonne, 31062 Toulouse, France.
A two-axis thrust stand is developed and validated experimentally, enabling direct and simultaneous measurements of two components of the thrust vector of an electric thruster. It is made of two piled-up single-axis stages, each having a hanging deformable parallelogram geometry. A mass deposition calibration method is used to calibrate the thrust stand, including crosstalk between axes.
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