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Online health forums are increasingly used by patients to get information and help related to their health. However, information reliability in these forums is unfortunately not always guaranteed. Obviously, consequences of self-diagnosis may be severe on the patient's health if measures are taken without consulting a doctor. Many works on trust issues related to social media have been proposed, but most of them mainly focus only on the structure part of the social network (number of posts, number of likes, etc.). In the case of online health forums, a lot of trust and distrust is expressed inside the posted messages and cannot be inferred by only considering the structure. In this study, we rather suggest inferring the user's trustworthiness from the replies he receives in the forum. The proposed method is divided into three main steps: First, the recipient(s) of each post must be identified. Next, the trust or distrust expressed in these posts is evaluated. Finally, the user's reputation is computed by aggregating all the posts he received. Conducted experiments using a manually annotated corpus are encouraging.
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PLOS Glob Public Health
September 2025
Department of Pediatrics, University of Colorado, Aurora, Colorado, United States of America.
Children affected by armed conflict suffer devastating physical, emotional, and social harm. War uproots families, forcing many to flee as refugees or internally displaced persons, while others remain trapped in dangerous environments. In these crises, children face disproportionate risks-violence, exploitation, disrupted education, and collapsed healthcare systems.
View Article and Find Full Text PDFJ Immunother Precis Oncol
August 2025
The Christie NHS Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, United Kingdom.
Introduction: Patients with advanced solid tumors may be considered for early phase clinical trials investigating the safety, tolerability, and dosing of experimental therapies. Optimizing participant selection is critical to maximize clinical benefit and meet trial endpoints with fewer participants. One in six participants does not meet routine life expectancy requirements (>3 months), highlighting the need for improved prognostication.
View Article and Find Full Text PDFOpen Forum Infect Dis
September 2025
Division of Public Health, Infectious Diseases, and Occupational Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA.
Background: The incidence, epidemiology, and clinical characteristics of enterococcal bloodstream infection (BSI) have not previously been studied on a population-based level in the United States.
Methods: We utilized the Expanded Rochester Epidemiology Project medical records linkage system to conduct a contemporary 5-year, retrospective, population-based study of monomicrobial enterococcal (ME) BSI among adult residents of 8 counties in southeast Minnesota from January 1, 2018 to December 31, 2022.
Results: A total of 109 cases of ME-BSI were identified.
Open Forum Infect Dis
September 2025
Department of Epidemiology, University of Washington, Seattle, Washington, USA.
Accurate point-of-care tools are needed to detect early nonadherence to daily HIV regimens and support timely transitions to long-acting options. Emerging evidence suggests that females may require higher adherence than males to achieve equivalent protection. Our next-generation urine tenofovir assay showed high accuracy across sexes but lower urine drug levels among female participants.
View Article and Find Full Text PDFPost Reprod Health
September 2025
Department for Infection and Population Health, Insititute for Global Health, University College London, London, UK.
ObjectiveWe are developing a menopause education and support programme, 'InTune', using co-design that includes focus groups and workshops. We have identified the need for two key interventions: one aimed at raising general awareness, , and another to support those currently experiencing menopause symptoms. This survey aims to reach a broader audience to better understand their needs and preferences around menopause education and support.
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