Development of grouped icEEG for the study of cognitive processing.

Front Psychol

Vivian Smith Department of Neurosurgery, University of Texas Health Science Center at Houston Houston, TX, USA ; Texas Medical Center, Mischer Neuroscience Institute, Memorial Hermann Hospital Houston, TX, USA.

Published: August 2015


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Article Abstract

Invasive intracranial EEG (icEEG) offers a unique opportunity to study human cognitive networks at an unmatched spatiotemporal resolution. To date, the contributions of icEEG have been limited to the individual-level analyses or cohorts whose data are not integrated in any way. Here we discuss how grouped approaches to icEEG overcome challenges related to sparse-sampling, correct for individual variations in response and provide statistically valid models of brain activity in a population. By the generation of whole-brain activity maps, grouped icEEG enables the study of intra and interregional dynamics between distributed cortical substrates exhibiting task-dependent activity. In this fashion, grouped icEEG analyses can provide significant advances in understanding the mechanisms by which cortical networks give rise to cognitive functions.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508923PMC
http://dx.doi.org/10.3389/fpsyg.2015.01008DOI Listing

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